thebillsfan

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Dec 22, 2008
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I hear it in organic chemistry all the time. Not something I think we need to know, but I want to know it!
 

loveoforganic

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Jan 30, 2009
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"Neat" means you run your reaction without a solvent. For example, I ran a reaction where benzaldehyde was one of the reactants. Benzaldehyde is a liquid at room temp, and it also was able to solvate my other reactants/catalyst. For this reason, the reaction was just run in stoichiometric benzaldehyde ("neat") as opposed to in a solvent. It provides better atom efficiency.
 

sleepy425

10+ Year Member
Mar 6, 2008
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Resident [Any Field]
"Neat" means you run your reaction without a solvent. For example, I ran a reaction where benzaldehyde was one of the reactants. Benzaldehyde is a liquid at room temp, and it also was able to solvate my other reactants/catalyst. For this reason, the reaction was just run in stoichiometric benzaldehyde ("neat") as opposed to in a solvent. It provides better atom efficiency.
benzaldehyde also smells amaaaazing