What is a "neat" solution?

[thebillsfan]

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I hear it in organic chemistry all the time. Not something I think we need to know, but I want to know it!

 

[loveoforganic]

"Neat" means you run your reaction without a solvent. For example, I ran a reaction where benzaldehyde was one of the reactants. Benzaldehyde is a liquid at room temp, and it also was able to solvate my other reactants/catalyst. For this reason, the reaction was just run in stoichiometric benzaldehyde ("neat") as opposed to in a solvent. It provides better atom efficiency.

 

[unDRdog]

room temp...jk...thats only with scotch!!!

 

[sleepy425]

"Neat" means you run your reaction without a solvent. For example, I ran a reaction where benzaldehyde was one of the reactants. Benzaldehyde is a liquid at room temp, and it also was able to solvate my other reactants/catalyst. For this reason, the reaction was just run in stoichiometric benzaldehyde ("neat") as opposed to in a solvent. It provides better atom efficiency.

benzaldehyde also smells amaaaazing

 

[loveoforganic]

So true, freshly distilled.... Mmmmmmm