For most of your classes you won't need anything more than a scientific calculator. Something with sin/cos/tan, square root, log/ln, and exponents should cover you. You can find something like that for really cheap (under $10). I really like TI calculators and haven't been pleased with other brands I've had. For calculus, you might be required to get a graphing calculator. For that I would go with the TI-83. Most people have those, so any function your teacher talks about on the calculator you will be able to follow right along with. All of the TIs are pretty similar so you could probably get by with another model too. TI-83s are also useful for statistics, which you will probably end up taking if not as a pre-pharm, you will in pharm school.