I give a little background to preface so you can determine how well this does or does not relate to your situation. Before I started studying I read through last year's thread and it seemed that everyone said that the high yield material was cardiovascular phys and pharm, neuro, psych drugs, and then a whole bunch of OB that felt like it was way too advanced for being level I questions. Anyway, about 3 months ago I took COMSAE A and got a 389. I started studying here and there during the last quarter and covered the different sections of FA in conjunction with any coursework. I had originally purchased a bunch of different resources that I intended to use, but ultimately all I used was FA, Savarese, Combank and went through Goljan audio 2.5 times. 10 days before COMLEX I took COMSAE B and got a 451. At this time I was averaging about 58% on COMBANK. In the time between then and the test I went through First Aid again (for a total of four times), went through Savarese again (had gone through thoroughly the first time and went for more quick high-yield the second time) and then finished off COMBANK (had roughly 3/4 of it left). By the time I was finishing COMBANK I felt like I was smoking the questions and was probably averaging high 70s to low 80s, raising my total to 66+%. I felt pretty confident and got really used to the COMBANK format and knew what they were getting at immediately, which was helpful for probably 30-50% of COMLEX but not as helpful for the rest as the questions were much more vague and difficult to reason through.
As far as test day, I got a whole bunch of autonomic level questions in addition to getting a couple that were very indirectly asking autonomics but it took you a while to figure that out. I got a lot of OMM relevant anatomy (got muscle attachments for muscle energy on ribs in 2 different questions) which a couple of the questions were difficult but the answers options made it more obvious. I only had one cranial strain pattern question, but a few that asked things like which bone may be dysfunctional given a set of symptoms (no more than 3 questions), got condylar compression twice needing to know which nerve (hypoglossal) and sucking in a child. A few sacral dx qs. A few physical findings questions on the spine. A few questions on mechanics, including one that included chiropractic terminology (subluxation) as a possible answer to what type of mechanics something was. The OB questions I felt were easy, at least in regard to how hard everyone made it sound from last year. Pretty straight forward. Biochem questions were a little more difficult since there were a few on some enzymes that I hadn't committed to memory. I really didn't get very many "what's the antibiotic tx" questions, maybe 4-5. Some things were indirectly tested but the antimicrobial therapy, at least in conjunction with a particular diagnosis, wasn't too well represented. For pharm I think that most everything was in first aid. I think I remember maybe one drug I hadn't seen, but based on it's name and similarities I was able to figure it out. Endocrine was pretty simple. Standard diabetes insipidus, SIADH, cushings, etc. 2 AIDS tx qs. A few straight up "age + symptoms = what's most likely bug?" Horrible pictures that were very blurry. Two questions on heterophile negative pharyngitis that were nearly the same. I don't think I saw one SLE question. Only one Chapman's. I think only one question on virology with regard to knowing something about the virus, everything else was just knowing clinical correlations. LOTS of questions about overdoses, toxicology, recreational drug use, symptoms of use/withdrawal, etc. A few psych drugs regarding mechanism. One differentiating typical vs. atypical antipsychotics. A couple differentiating first and second generation antihistamines. Knowing mechanism of heart drugs (e.g. nitrates reducing heart work via decreased preload vs. dilating coronary arteries). A handful of questions on gram staining and other micro techniques asking what the bug was. I think only 2-3 questions with BT, PT, PTT. That's all I can think of right now.