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According to Kaplan if a lysosome ruptures within a cell, hydrolytic enzymes of the lysosome would digest organelles and kill the cell. But I read in a cell bio text that hydrolytic enzymes of the lysosome are active only in the low pH of a lysosome. The usual pH of the cytoplasm is around 7.2. Would this not deactivate the hydrolytic lysosomal enzymes? If anyone can clarify this a little further, please do.
Thanks
Thanks