anti 0 antibody

[aysenur]

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do AB blood group patients have anti 0 antibody, according to my knowledge they don't, so why they do not have it?

 

[Luka75]

They don't have anti-O because O is not an antigen in and of itself, it's just the lack of A or B.

 

[aysenur]

I am trying to say that
0 Ag +Galactose= B Ag or
0 Ag+N-Acetylgalactosamine=A Ag
we have a kind of 0 antigen molecule on our erytrocytes surface, if AB blood group patients don't have 0 Ag they should be producing anti 0 antibody, so why they do not form it

 

[Luka75]

I am trying to say that
0 Ag +Galactose= B Ag or
0 Ag+N-Acetylgalactosamine=A Ag
we have a kind of 0 antigen molecule on our erytrocytes surface, if AB blood group patients don't have 0 Ag they should be producing anti 0 antibody, so why they do not form it

Are you talking about the precursor form from which A and B develop?

 

[togaedere]

It doesn't seem like you're understanding the major blood groups. O is not an antigen, it corresponds to null or no antigen. Of course, it doesn't mean that the erythrocyte doesn't have Rh or other minor antigens, it just lacks the A or B. Therefore, in the serum there are antibodies to both A and B. With AB blood, there are no (major) antibodies produced. Again, O is not an antigen so no antibody would be produced.

I am trying to say that
0 Ag +Galactose= B Ag or
0 Ag+N-Acetylgalactosamine=A Ag
we have a kind of 0 antigen molecule on our erytrocytes surface, if AB blood group patients don't have 0 Ag they should be producing anti 0 antibody, so why they do not form it

 

[Luka75]

It doesn't seem like you're understanding the major blood groups. O is not an antigen, it corresponds to null or no antigen. Of course, it doesn't mean that the erythrocyte doesn't have Rh or other minor antigens, it just lacks the A or B. Therefore, in the serum there are antibodies to both A and B. With AB blood, there are no (major) antibodies produced. Again, O is not an antigen so no antibody would be produced.

My point exactly.

 

[aysenur]

thank you,now I understood