Biology Question, ( Endocrine )

[bluesolic]

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Ok, Who make Insulin ?

Pancrease? or Liver ?


The mechanism in the body is so so complicated..

it seems like nothing is making something independently, but the question in the book always ask about this kind of question and this makes me crazy...

 

[tomhrxbfg]

the beta cell in the islet of langerhans in pancreas makes insulin...

 

[bluesolic]

one more question....

if the body doesn't have enough sugar in the blood,

Glucagon is initiated ?

Or

Glucocorticoid is initiated ?


it seems like they work the same..


What is the difference btwn them ???

why do we use Glucagon instead of Glucocorticoid ???

 

[Mr. Thirsty]

Glucagon and glucocorticoids are both antagonistic to insulin. They are all used to increase blood glucose but glucagon focuses on the liver. Corticoids cone from the adrenal "cor"tex. You shouldn't have to know anything more specific than that about them.

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[joeeeey3]

I don't mean to hijack your thread but, I have a similar question:
whats the difference b/w fibrin and platelets??

 

[dentalwannabe]

whats the difference b/w fibrin and platelets??

Both are involved in clotting, but size is different for one thing. Fibrin is a protein while platelets are "cell fragments" (with no nucleus).

 

[bluesolic]

Glucagon and glucocorticoids are both antagonistic to insulin. They are all used to increase blood glucose but glucagon focuses on the liver. Corticoids cone from the adrenal "cor"tex. You shouldn't have to know anything more specific than that about them.

Sent from my DROIDX using SDN Mobile

what does that mean, " Focuses on the LIVER? "

Thanks for the answer

 

[dentalwannabe]

The liver is where there are some store of glycogen. (There are also some in muscles.) Glucagon acts on the liver to make it break up stored glycogen into smaller saccharides like glucose. This raises blood glucose.

Question I came up with while answering this last one: Does glucagon also promote gluconeogenesis by the liver???

 

[bluesolic]

The liver is where there are some store of glycogen. (There are also some in muscles.) Glucagon acts on the liver to make it break up stored glycogen into smaller saccharides like glucose. This raises blood glucose.

Question I came up with while answering this last one: Does glucagon also promote gluconeogenesis by the liver???

Thanks for the answer

and I think every rxn from something to glucose is called xxxxneogenesis..


well, here is another question..

if I used up all glucose,

fat goes to glucose first ?

or Amino acide goes to glucose first ?


or they all become glucose ?


or there is some kind of ratio like 60:40 fat😛rotein, something like this...

 

[dentalwannabe]

I am not sure that glycogen breakdown is classified as gluconeogenesis.

Other opinions?

 

[dentalwannabe]

I believe it's fat, then protein. (Of course if you've ever asked someone trying to lose weight, they would prob say it feels like the other way around.)

 

[tomhrxbfg]

Fat is broken down first, undergoing beta oxidation to make Acetyl CoA. Protein is used when no glucose or fats are available (muscle break down).

wikipedia:
Glycogenolysis (also known as "Glycogenlysis") is the break down of glycogen to glucose-1-phosphate and glucose.

Gluconeogenesis (abbreviated GNG) is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as lactate, glycerol, and glucogenic amino acids.

 

[vlaura0214]

Glycogenesis - formation of glycogen (from glucose)
Glycogenolysis - breakdown of glycogen (to form glucose)

Gluconeogenesis - formation of glucose
Glycolysis - breakdown of glucose

 

[dentalwannabe]

tomhrxbfg, thank you!
and vlaura0214 too!

That makes perfect sense. It's all in the name : ).

 

[vlaura0214]

Yeah, the only one that is confusing is glycolysis with gly- instead of glu-, but just remember the process in cellular respiration! Good luck studying. 🙂