Cliff's Bio Translation

[osimsDDS]

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Hey I was going through Cliff's AP bio and I came across something at the top of pg 114 for those who have the book...

"After transcription, the mRNA, tRNA, and ribosomal subunits are transported across the nuclear envelope and into the cytoplasm."

I think this is wrong, they are saying that tRNA is produced in the nucleolus but I know for a fact it is made in the cytoplasm...rRNA is made in the nucleolus and therefore it would be found in the nucleur envelope but tRNA I dont think so...

What do you guys think...

 

[Thundercatz]

I believe all rna's are made in the nucleolus.

 

[bumpski20]

I thought all RNA's are synthesized in the nucleus and the rRNA is processed in the nucleolus.

 

[113zami]

it says in campbell page 305 (5th edition) that "in a eukaryotic cell, tRNA, like mRNA, is made in the nucleus and must travel from the nucleus to the cytoplasm, where translation occurs".
so I guess from this sentence its clear that tRNA is made in the nucleus

also in kaplan subject test 1

#5 the question is: which of the following is a characteristic of tRNA:
a)it is a long filament of RNA
b) it is produced in the nucleolus
c)it has a polyA tail
d) it has some short double stranded segment

and the answer is D not B, so I guess from that we can conclude that the tRNA is strictly made in the nucleus not the nucleolus or the cytoplam

 

[Mstoothlady2012]

it says in campbell page 305 (5th edition) that "in a eukaryotic cell, tRNA, like mRNA, is made in the nucleus and must travel from the nucleus to the cytoplasm, where translation occurs".
so I guess from this sentence its clear that tRNA is made in the nucleus

also in kaplan subject test 1

#5 the question is: which of the following is a characteristic of tRNA:
a)it is a long filament of RNA
b) it is produced in the nucleolus
c)it has a polyA tail
d) it has some short double stranded segment

and the answer is D not B, so I guess from that we can conclude that the tRNA is strictly made in the nucleus not the nucleolus or the cytoplam

you mean which of the following is not a characteristic of tRNA?

 

[HoangDDS]

it says in campbell page 305 (5th edition) that "in a eukaryotic cell, tRNA, like mRNA, is made in the nucleus and must travel from the nucleus to the cytoplasm, where translation occurs".
so I guess from this sentence its clear that tRNA is made in the nucleus

also in kaplan subject test 1

#5 the question is: which of the following is a characteristic of tRNA:
a)it is a long filament of RNA
b) it is produced in the nucleolus
c)it has a polyA tail
d) it has some short double stranded segment

and the answer is D not B, so I guess from that we can conclude that the tRNA is strictly made in the nucleus not the nucleolus or the cytoplam

thanks for posting that 113zami. I also felt that it was D.

 

[113zami]

you mean which of the following is not a characteristic of tRNA?

nope, just checked it again, it says which of the following is a characteristic of tRNA? unless I have an older version of kaplan's subject tests and they changed something over the past 2 years...anyone with a more recent version feel free to confirm/reject

 

[Albuterol]

didnt feel like creating a new thread but...hopefully someone reads this
i have a question about the direction that translation is read and translated....

replication-read 3-->5...written 5--->3
transcription-read 3--5...written 5--->3

translation-read 5'-->3'...and translated 3--->5?
im not too sure about this ...i think it makes sense because the 5' end of the newly synthesized mrna is the first to be exposed to the ribosomes...if someone could clarify this please.

 

[Mstoothlady2012]

didnt feel like creating a new thread but...hopefully someone reads this
i have a question about the direction that translation is read and translated....

replication-read 3-->5...written 5--->3
transcription-read 3--5...written 5--->3

translation-read 5'-->3'...and translated 3--->5?
im not too sure about this ...i think it makes sense because the 5' end of the newly synthesized mrna is the first to be exposed to the ribosomes...if someone could clarify this please.

I think translation starts at 5' end. Remember 5' cap has fmet/met which initiates translation. 3' has poly-A tail which forms A:U base pair with tRNA which allows the formation of hairpin loop to terminate translation So yea translation is from 5' ---> 3'. I am not sure if that's what you meant by written...

 

[osimsDDS]

I think translation starts at 5' end. Remember 5' cap has fmet/met which initiates translation. 3' has poly-A tail which forms A:U base pair with tRNA which allows the formation of hairpin loop to terminate translation So yea translation is from 5' ---> 3'. I am not sure if that's what you meant by written...

translation starts at the 5' cap because the 5' end is equipped with GTP that was put on at the RNA processing stage, therefore thats where the rRNA subunits attach to and start translation...translation is read on the mRNA 5' to 3' direction...