Probably not. I listed gaming under 'Leisure Activities' in TMDSAS and have received multiple interviews, and some of my interviewers even brought it up positively.
But it's worth noting I usually back up 'gaming' with the idea that my experience with MMOs has helped me develop in to the person I am today (ex. I first learned leadership qualities at the helm of various online guilds, talking with people on voice servers helped me overcome my middle/high school shyness, etc.). Gaming is also an 'involved' hobby - you're doing something and it can potentially involve much critical thinking. I'm not really sure it would be wise to follow up watching HBO with how you formed as a person.
Additionally, if you're talking about AMCAS, you only get 15 spots. I would strongly recommend wasting a spot on something trivial; TMDSAS has no limit (as far as I am aware).