hip injection, with 80mg Depo?

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jonnylingo

Junior Member
15+ Year Member
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Typically I inject 40mg. Never had AVN complication, knock on wood.

Got a request from Ortho to perform interarticular hip injection with 80mg of Depo. If fails, then surgery is next step.

Do it? Or go with my usual 40mg?

Any input appreciated.
 
I've never seen any good literature on corticosteroid dose with IA corticosteroids.

But the fact remains that AVN should not be a concern of yours since the patient will go on to THA if the injection doesn't work regardless.
 
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There are a few articles on this kind of thing, for different joints. 40 or 80 should be safe, and are relatively common doses.

http://www.ncbi.nlm.nih.gov/pubmed/16873380
http://www.ncbi.nlm.nih.gov/pubmed/23507791
http://www.ncbi.nlm.nih.gov/pubmed/22030233
http://www.ncbi.nlm.nih.gov/pubmed/26233499

the largest n of these was 120. None showed an increase in complications, but with that small of a sample size, we would not expect to see an increase (since the complication rate is so low in all intra articular joint injections)