For anyone that doesn't know, I do exclusively inpatient hospice. Most all my patients die, but then again, all of our patients die eventually, it's all just in the timing. Mine just tend to die sooner. My goal is that they don't suffer, but I don't influence the timing. (Seriously, that's up to the patient. I've seen way too many times people wait for the daughter from Michigan to show up, and 10 minutes later, they go. Happened again this afternoon, except the daughter seriously had just arrived from Missouri. He made it about an hour.) Anyway...
I cranked up a fentanyl drip yesterday to a 1000mcg/hr with a 500 mcg bolus.
(It was 300/200 that morning... but it wasn't working. Rapid titrating all day.) Aaaand she was awake, alert and still pretty miserable. The feculent vomiting and the new peritoneal signs probably heralding the end showed up mid afternoon. UG.
After a couple hours I threw in the towel and rotated to dilaudid + ketamine. And she was hitting the bolus herself before that. It finally worked. Cervical cancer is a bitch.
But that's another story for another day.
My personal record is a dilaudid infusion at 40 mg/hr with a 20 mg bolus q10 min (and she was using it a lot) plus ketamine at 30mg/hr plus lidocaine 200mg/hr plus some ativan around the clock and other crap. And she was walking around like that. Not walking well, granted, but walking. I think she perfed too, but definitely had sacral plexus involvement, and when you're only 36, well, it's tremendous what the body can tolerate. Another cervical cancer actually.
I routinely have "compassionate" extubations survive beyond the minutes or hours that the inpatient teams think they're going to live. Sometimes days. Occasionally longer. (Why did they get intubated in the first place? Just airway protection? Hypoxia? Hypercarbia? Sometimes these folks just keep chugging along.) Humans are truly amazing. The suffering they can endure is also amazing.
Also FWIW, I don't have a lot of kids, but you all know that chronic parents are in a different category, and yeah, they wait. Also, once patients get to be 95 or older, all bets are off. You make it that long, you're gonna live forever. I have a 99 year old on my service right now who may never die. He's cachectic as all get out, but by golly, we figure he's enjoying all this attention and that's why he's sticking around.