I don't know where to ask this...curious

[codered7]

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This may be a stupid question..but

How come drugs have common endings like sodium, bitartrate, tartrate, sulfate, HCL, succinate... a couple others.

Levothyroxine sodium, hydrocodone bitartrate, metoprolol tartrate, magnesium sulfate, metformin HCL, metoprolol succinate...are examples.

But I see that these show up alot, why are they so commonly used in combinations? Make the drug more stable? I don't remember learning this in class. Someone please explain thanks!

 

[ValeRx]

Salts.

 

[nnguyenc]

pre-pharm i presume?

 

[PharmasaurusRx]

pre-pharm i presume?

You'd be surprised, actually. I had a classmate ask me this same question weeks ago and we're P1s. It was never specifically taught to us.

 

[Quiksilver]

This may be a stupid question..but

How come drugs have common endings like sodium, bitartrate, tartrate, sulfate, HCL, succinate... a couple others.

Levothyroxine sodium, hydrocodone bitartrate, metoprolol tartrate, magnesium sulfate, metformin HCL, metoprolol succinate...are examples.

But I see that these show up alot, why are they so commonly used in combinations? Make the drug more stable? I don't remember learning this in class. Someone please explain thanks!

helps dissolution and as a result, bioavailability

 

[PumpkinSmasher]

I like salt, makes my food taste good so it must make my drugs taste good too.

 

[ValeRx]

Also, use some common sense. If something says HCl by it, what the heck do you think it does?

Hint: Has to do with pH......

 

[Quiksilver]

Also, use some common sense. If something says HCl by it, what the heck do you think it does?

Hint: Has to do with pH......

Don't be a douche. Lay off the dude, he was curious enough to ask. Instead of promoting learning, the sole purpose of this boards, you are cutting it down. And you are going to treat people who have less knowledge and less bravery to ask questions like this and your job is going to educate these people. And you aren't even a pharmacy student yet so I wouldn't talk like you are the ****. We all have to start somewhere and if he's a prepharmer, you aren't exactly peaking his interest.

for your info it has more to do with increasing solubility so it can dissolve in the GI tract then it does with pH, it enhances dissolution. It isn't hydrochloric acid, its a hydrochloride salt, but someone with your knowledge would apparently know that.🙄

 

[ffpickle]

Don't be a douche. Lay off the dude, he was curious enough to ask. Instead of promoting learning, the sole purpose of this boards, you are cutting it down. And you are going to treat people who have less knowledge and less bravery to ask questions like this and your job is going to educate these people. And you aren't even a pharmacy student yet so I wouldn't talk like you are the ****. We all have to start somewhere and if he's a prepharmer, you aren't exactly peaking his interest.

for your info it has more to do with increasing solubility so it can dissolve in the GI tract then it does with pH, it enhances dissolution. It isn't hydrochloric acid, its a hydrochloride salt, but someone with your knowledge would apparently know that.🙄

lol

 

[duck832000]

Also, use some common sense. If something says HCl by it, what the heck do you think it does?

Hint: Has to do with pH......

LOL you're a pre-pharm and you're acting like a prof already? Save that attitude for later when you are a pharm prof or pharmacist preceptor. Even if you are one of those, you still piss people off with such answer.

 

[Vitamin K]

He/she might be pre-pharm, but this is something that's covered in organic chem. At least in our program, organic chem is a pre-pharm class. I'm a little disappointed that a pharmacy student doesn't know the answer to this question...(yes, it's good to ask, but has your program failed you that bad??)

 

[ValeRx]

Don't be a douche. Lay off the dude, he was curious enough to ask. Instead of promoting learning, the sole purpose of this boards, you are cutting it down. And you are going to treat people who have less knowledge and less bravery to ask questions like this and your job is going to educate these people. And you aren't even a pharmacy student yet so I wouldn't talk like you are the ****. We all have to start somewhere and if he's a prepharmer, you aren't exactly peaking his interest.

for your info it has more to do with increasing solubility so it can dissolve in the GI tract then it does with pH, it enhances dissolution. It isn't hydrochloric acid, its a hydrochloride salt, but someone with your knowledge would apparently know that.🙄

Cutting down the promotion of learning? Hardly. In fact I'm doing quite the opposite. Maybe you like to hold peoples hand and give them everything as opposed to having them do a little research on their own? I would argue that YOU are the one cutting down the learning process by giving out answers.

Maybe we should rename this forum "Ask Quiksilver", and you give out the answers to every question. I'll leave you to it.

While you're at it, hop on over to Pre-Pharm and start telling everybody how to answer all their possible interview questions.

 

[ValeRx]

LOL you're a pre-pharm and you're acting like a prof already? Save that attitude for later when you are a pharm prof or pharmacist preceptor. Even if you are one of those, you still piss people off with such answer.

😴

 

[Jdario86]

LOL. ValueUC is getting whipped. You should save the witty bantering for star trek conventions.

Anywho, I think there's no such thing as a stupid question in the sciences. If you don't feel like answering their question, just don't answer. period.

But yes - these are all salts.

 

[Quiksilver]

Cutting down the promotion of learning? Hardly. In fact I'm doing quite the opposite. Maybe you like to hold peoples hand and give them everything as opposed to having them do a little research on their own? I would argue that YOU are the one cutting down the learning process by giving out answers.

Maybe we should rename this forum "Ask Quiksilver", and you give out the answers to every question. I'll leave you to it.

While you're at it, hop on over to Pre-Pharm and start telling everybody how to answer all their possible interview questions.

Because your answer really encourages research. not to mention the fact that you yourself were wrong! Maybe you should take some of your own advice and do some research yourself before you answer what you call a dumb question. Maybe next time you won't look like an idiot. Which by the way, your comments just continue to be even more insightful than the last.

Your ignorance is bigger then your arrogance and you have a lot to learn. The fact is that you are not a pharmacy student yet. maybe you should return to the pre-pharm forum where you belong and continue to your advice giving there, since its so much better then mine. You certainly have a better grasp in knowledge in pharmacy and how to practice then me.🙄

I on the other hand have a conscience and would prefer to spoon feed information rather then to put someone's life on the line for the sake of making an example. Grow up, pop that ego that keeps you on Cloud Nine because it won't do you any good as a pharmacist.

 

[Quiksilver]

and one other point, no one is forcing you to reply to a thread that insults your high level intelligence. If you think the question is below you and a waste of time you can just move on to the next thread instead of bashing someone that has a question and wants to learn.

 

[ffpickle]

and one other point, no one is forcing you to reply to a thread that insults your high level intelligence. If you think the question is below you and a waste of time you can just move on to the next thread instead of bashing someone that has a question and wants to learn.

👍

 

[ValeRx]

and one other point, no one is forcing you to reply to a thread that insults your high level intelligence. If you think the question is below you and a waste of time you can just move on to the next thread instead of bashing someone that has a question and wants to learn.

Perhaps you should reread my responses. At no time did I say that it was a dumb question. Another would be my first response, which was in fact the correct answer to the OP's question. Thirdly, the only one looking like an idiot here is yourself. My ego? The only one here with the superiority complex is you with your "just a pre-pharm" statements. Keep using them because I certainly feel belittled and put in my place every time you say it.

 

[ffpickle]

Still, the question asked originally doesn't even make much sense?

"why are things named the way they are?"

huh?

 

[ffpickle]

On a somewhat related note, people should learn to answer stupid questions without sounding like a jerk. It's a characteristic you need as a pharmacist.

 

[PharmaTope]

Cutting down the promotion of learning? Hardly. In fact I'm doing quite the opposite. Maybe you like to hold peoples hand and give them everything as opposed to having them do a little research on their own? I would argue that YOU are the one cutting down the learning process by giving out answers.

Maybe we should rename this forum "Ask Quiksilver", and you give out the answers to every question. I'll leave you to it.

While you're at it, hop on over to Pre-Pharm and start telling everybody how to answer all their possible interview questions.

you are everything that is wrong with pharmacy. pharmacy happens to have a lot of douches like you.

so why are you going into pharmacy? it clearly is not because you like helping people.

 

[Jdario86]

you are everything that is wrong with pharmacy. pharmacy happens to have a lot of douches like you.

so why are you going into pharmacy? it clearly is not because you like helping people.

🤣

 

[ValeRx]

you are everything that is wrong with pharmacy. pharmacy happens to have a lot of douches like you.

so why are you going into pharmacy? it clearly is not because you like helping people.

Indeed. How I come across here is CLEARLY indicative of how I treat people in real life.

 

[Jdario86]

Indeed. How I come across here is CLEARLY indicative of how I treat people in real life.

Point taken. You must be worse in real life.

 

[Quiksilver]

Perhaps you should reread my responses. At no time did I say that it was a dumb question. Another would be my first response, which was in fact the correct answer to the OP's question. Thirdly, the only one looking like an idiot here is yourself. My ego? The only one here with the superiority complex is you with your "just a pre-pharm" statements. Keep using them because I certainly feel belittled and put in my place every time you say it.

you don't need to say directly the question was dumb. Its inferred by your 2nd response in this thread . everyone else said the exact same thing. Or do you look at everyone else as if they are the ones with the problem? You are alone on this one. Face it, your comments were childish, and egotistical, you could have chosen your comments more wisely and been less of a douche. Your actions prove how big your ego is, you cant admit your fault even when everyone else sees it. Your job as a pharmacist is to teach people less knowledgeable then you, I suggest not talking to them in a similar fashion.

You are incorrect about the wonderful hint you gave the OP; it has little to do with pH; more dissolution. Nice.

My problem is not that I have an ego, I have a problem with people think that they are the **** and blast people who had an honest question. I replied to you to prove a point, you don't know it all and you shouldn't treat people that know less then you with such an attitude. I turn the tables and treat you the way you treated that comment and now its not so fun. I know I don't know it all, I don't claim to. I am not a pharmacist and I have a lot to learn. I can admit that and learn from my experiences. Can you?

Point taken. You must be worse in real life.

either that or he's trying to be a big man on the internet

 

[ValeRx]

either that or he's trying to be a big man on the internet

Just like you, big brother.

 

[fenixtnlfan]

Please get back on topic and stop the name calling.

 

[dreezy10]

Haaahaaaa, This thread is entertaining!!!!

I'm a pre pharmer too, but the pharmacy threads are much more fun!!!!

there's no douches and idiots flying across the board over there!!!!!

Dreezy10

And the funniest thing is............ if you search for the word douche, THIS THREAD COMES UP!!!

😆😆😆😆😆😆😆😆😆😆

 

[Brixius]

I find it is very hard to ask a question in here and not have somebody treat you like you're an idiot. There seems to be a lot of jerks on this board ... everybody is trying to prove something to each other.

Let us take the following line of thought into practice when formulating our replies: there are a lot of things that I know that you don't, as there as are lot of things that you know that I don't. The world of pharmacology has a huge amount of information in it and I think we'd all do better if we don't pretend that we know everything -- even if something seems basic to us.

This board would be a lot better if we all practiced some civility.

 

[dreezy10]

I find it is very hard to ask a question in here and not have somebody treat you like you're an idiot. There seems to be a lot of jerks on this board ... everybody is trying to prove something to each other.

Let us take the following line of thought into practice when formulating our replies: there are a lot of things that I know that you don't, as there as are lot of things that you know that I don't. The world of pharmacology has a huge amount of information in it and I think we'd all do better if we don't pretend that we know everything -- even if something seems basic to us.

This board would be a lot better if we all practiced some civility.

This is a great idea, but in reality, everyone is not civil, we all must deal with disrespectful people at one point. And it is impossible to make every single person here be civil.

******PLUS, a civil person's post is not as fun to read as a jerk's post right?***********

 

[Fuzzychickens]

Salts are there so a drug company can make the same drug with a different salt and patent it and send drug reps to doctors offices to get them to prescribe the "new" drug that costs 10 times as much.

Oh yea, they also help dissolution and bioavailability.

 

[Quiksilver]

Salts are there so a drug company can make the same drug with a different salt and patent it and send drug reps to doctors offices to get them to prescribe the "new" drug that costs 10 times as much.

Oh yea, they also help dissolution and bioavailability.

Somewhat true. By changing the salt, you change the kinetics of the drug, in particular the absorption. The degree of a solubility of a salt depends on the biochemistry of the drug molecule itself (degree of hydrophobicity) and ion thats attached to the molecule. Sometimes changing the salt will delay dissolution slightly or delay uptake from the gut and make a product extended release.

 

[Brixius]

This is a great idea, but in reality, everyone is not civil, we all must deal with disrespectful people at one point. And it is impossible to make every single person here be civil.

******PLUS, a civil person's post is not as fun to read as a jerk's post right?***********

It is impossible, but there seems to be a large percentage of jerks on this board. Everybody is trying to prove something -- I'm starting to believe this pharmacist inferiority complex theory. Not that I disagree with Quik's handling of the situation; I say we jump on everybody trying to belittle someone else. Wouldn't that be entertaining?

 

[evilolive]

Perhaps you should reread my responses. At no time did I say that it was a dumb question. Another would be my first response, which was in fact the correct answer to the OP's question. Thirdly, the only one looking like an idiot here is yourself. My ego? The only one here with the superiority complex is you with your "just a pre-pharm" statements. Keep using them because I certainly feel belittled and put in my place every time you say it.

Well, I felt belittled for you 🙁