Ok, this could be long…The 2+4 program would be for students who go to a university that has a College of Pharmacy. They do their pre-reqs the first two years and then they have to re-apply to the professional part of the program which would be years 3-6. I believe they would have priority over other students applying to the program who did their pre-reqs somewhere else but they are not guaranteed anything. At 0-6's the student does the pre-reqs at the school and is guaranteed a seat in the college of pharmacy provided they maintain a certain GPA along with some other requirements. So, the key word here is "guaranteed". This website is a great starting point and you may need it to apply to certain schools:
http://www.pharmcas.org/advisors/admissionsprocess.htm
As for CC, I personally think CC's get a bad rep. I've taken classes at a CC but they weren't sciences. However, I thought both of them were taught extremely well and I didn't get "short-changed" anything in the learning experience. The biggest difference between CC and a 4-year University is the intensity of courses in my opinion, which is why I think COP's look down on them sometimes. If the class meets the pre-req requirement they will most likely accept it but that could play a role on whether or not they accept you or someone who has taken all their pre-reqs at a 4-year school. So, if you take the pre-reqs at a CC you would then apply to the COP's in which you have met their admission requirements. Every college is different, don't ask why. The pre-reqs may take you 2 years or more. If you were in a 2+4 or 0-6 it would be 2 b/c the curriculum is set up so that you have to get it done in 2 years and the classes you need will definitely be offered. At another school you may have to wait for certain classes to be offered or a spot in the class if it fills up. If you play around on PharmCAS you can find requirements for all the COP's and go from there. As far as applying to the east coast, I can't really help there. You'd have to make sure the schools you'd like to apply to will accept the credits, they'll probably want course descriptions. You can email these schools or contact them and ask them specifics…that's their job and it's not too early.
In my experience I have dealt with schools who will specifically tell you they'd rather you take the pre-reqs at a 4-year school. Obviously not every program feels this way and even the ones that do will not totally disregard your application. I also feel that a student in your situation is best fit for a 2+4 or 3-year accelerated. The reason is that unless a lot of kids fail or decide to quit the program at a 0-6, you have no chance of getting admitted. Some of these schools even say on their websites that they do not accept transfers due to lack of seats available. Hopefully this is a little clearer to understand but keep doing research and search the threads b/c there is probably a ton of info on this situation…best of luck.