IV Labetalol

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croissantlover

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I have few questions regarding this drug. So if the order for Labetalol is 10mg if systolic >160 and 20mg if systolic >180 how much mg do you give if BP reads 180/120?? Is there a certain BP range protocol for what dosage to start labetalol with?? And also is 20mg Labetalol huge enough to cause someone go at shock and not recover after. Katzung pharmacology says labetalol reduces BP by lowering systemic vascular resistance without significant alteration in heart rate or cardiac output.
 

allantois

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Are you a medical student?

You are not going to send a hypertensive person into shock by giving them Labetalol
 

ACSurgeon

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20 of labetalol is not a huge dose.

be careful of the intubated “sedated” patient who has a transient BP in the 180-200 related to poor pain control or sedation. For these patients 20 of labetalol can drop their pressure.
 
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croissantlover

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20 of labetalol is not a huge dose.

be careful of the intubated “sedated” patient who has a transient BP in the 180-200 related to poor pain control or sedation. For these patients 20 of labetalol can drop their pressure.
If the EKG show ischemic changes under this scenario with HR 160s and BP 180/120 what could be the likely reason? poor pain control or a cardiac pathology??
 

WheezyBaby

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PRN antihypertensives without a clear indication other than "blood pressure control" are lazy medicine. Those patients with a clear indication for blood pressure control should be on a titratable drip to minimize the likelihood of rapid swings you can see with bolus dosing, outside of settings like initial BP control in dissection, PRES, etc
 
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