Let's try again, join me for study group NBDE I may/June 2010

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blissonearth

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Hi friends, let's continue the closed thread here. No promoting any materials here, just prop some in doubt questions as our exam is approaching fast.
 
plasminisnotrequiredfor.jpg


i agree plasmin degrades the fibrin clot and so can be the answer.. but what about option 5 and 6?

proteolysis ?? it is also not related to blood clot formatin right?? and what about phospholipid?? why cant be answer 5 ot 6??

guys plz xplain...
 
plasminisnotrequiredfor.jpg


i agree plasmin degrades the fibrin clot and so can be the answer.. but what about option 5 and 6?

proteolysis ?? it is also not related to blood clot formatin right?? and what about phospholipid?? why cant be answer 5 ot 6??

guys plz xplain...

Blood clotting is mediated by a cascade of proteolytic activations that ensures a rapid and amplified response to trauma.

The calcium activates protein kinase C, which, in turn, activates phospholipase A2 (PLA2). PLA2 then modifies the integrin membrane glycoprotein IIb/IIIa, increasing its affinity to bind fibrinogen. The activated platelets change shape from spherical to stellate, and the fibrinogen cross-links with glycoprotein IIb/IIIa aid in aggregation of adjacent platelets.
 
preganglionic parasympathetic fibers pass through which of the following structures:
1. foramen ovale
2. stylomastoid
3. magnum and hypoglossal
4. sup orbital fissure and petrotympanic fissure

i thought it was only the sympathetic fibers that are found passing through the sup orbital fissure. could you make me understand this?
 
I hope this helps!! i am too bad at explaining!
Due to the many orders of magnitude spanned by Ka values, a logarithmic measure of the acid dissociation constant is more commonly used in practice. pKa, which is equal to −log10 Ka, may also be referred to as an acid dissociation constant:
http://en.wikipedia.org/wiki/PKa

Blood clotting is mediated by a cascade of proteolytic activations that ensures a rapid and amplified response to trauma.

The calcium activates protein kinase C, which, in turn, activates phospholipase A2 (PLA2). PLA2 then modifies the integrin membrane glycoprotein IIb/IIIa, increasing its affinity to bind fibrinogen. The activated platelets change shape from spherical to stellate, and the fibrinogen cross-links with glycoprotein IIb/IIIa aid in aggregation of adjacent platelets.


thank u guys.. good explanation... u r really helpful...
impcompletedestructiono.jpg


why not diabetes insipidus can be the ans?? its due to def of ADH... which is also secreted by pituitary gland.. complete destruction wont cause insipidus ?
 
thank u guys.. good explanation... u r really helpful...
impcompletedestructiono.jpg


why not diabetes insipidus can be the ans?? its due to def of ADH... which is also secreted by pituitary gland.. complete destruction wont cause insipidus ?

hey....
it says anterior pit in the question......insipidus caused by laack o ADH...which is secreted by post.pituitary..........:laugh:
 
jus relax mate......well my exams are in 2 weeks too.......do wat u can..revise......do occlusion veryy well....:idea:


i agree with u but the problem is u know i cannot take overload of questions .. now just 25 days remaining.. and still my physio biochem asda papers remaining.. so freaking out..

what u think? am i lagging back/? should i speeed up ??as i am still to do with this sub papers.. how many times u did asda papers?? and how many questions u do per day??

and about DA i agree.. i again have to revise it.. do u draw figures of occlusions? how do u solve them?? if u have good figures for it pl let me know....🙁🙁

good luck bro...
 
absorptionofcalciumfrom.jpg


y cant 5 be the answer?? parathyroid increases the calcium aborption from intestine..

the answer given is 4 in the answer key... confused...
 
i agree with u but the problem is u know i cannot take overload of questions .. now just 25 days remaining.. and still my physio biochem asda papers remaining.. so freaking out..

what u think? am i lagging back/? should i speeed up ??as i am still to do with this sub papers.. how many times u did asda papers?? and how many questions u do per day??

and about DA i agree.. i again have to revise it.. do u draw figures of occlusions? how do u solve them?? if u have good figures for it pl let me know....🙁🙁

good luck bro...



hey.....
ur on track.....u can be done wid the asda's soon.....fer occlusion i d suggest u read okeson..it helps to clear ur concepts.....as far as my asda questions r concerned-i m only doin the recent ones....not the first 4..don have time.....but u should do it........nd i d jus do the asda's once.... but i highly recommend okeson..!😀
 
can anyone tell me what are different type of heart blocks?? i mean 1st, 2nd, 3rd degree heart blocks?? and what we find in ECG?? actually i dont know what are different type of heart blocks .. just came across a question for 3rd degree heart block.. 🙂

what are the relevant findings of different HB????

guys help me out..

i feel my cardiac physiology is very bad.. all those isovolumetric and isotonic contractions and relaxations and other things dont go into my head.. 😀
 
can anyone tell me what are different type of heart blocks?? i mean 1st, 2nd, 3rd degree heart blocks?? and what we find in ECG?? actually i dont know what are different type of heart blocks .. just came across a question for 3rd degree heart block.. 🙂

what are the relevant findings of different HB????

guys help me out..

i feel my cardiac physiology is very bad.. all those isovolumetric and isotonic contractions and relaxations and other things dont go into my head.. 😀

First-degree AV block, or PR prolongation, in which the PR interval is lengthened beyond 0.20 seconds.
Second-degree AV block refers to a conduction block between the atria and ventricles. There are two distinct types of second-degree AV block, called Type 1 and Type 2. In both types, a P wave is blocked; but, in Type 1, there are increasing delays in each cycle before the omission, whereas, in Type 2, there is no such pattern.
Type 2 Second-degree AV block, also known as Mobitz II is almost always a disease of the distal conduction system (His-Purkinje System).
Third-degree AV block, also known as complete heart block, is a medical condition in which the impulse generated in the SA node in the atrium does not propagate to the ventricles.
  • The P waves with a regular P to P interval represents the first rhythm.
  • The QRS complexes with a regular R to R interval represent the second rhythm. The PR interval will be variable, as the hallmark of complete heart block is no apparent relationship between P waves and QRS complexes.
 
hiiiiiii frnz.....

can i too join the discussion here???????
at last i got my type thread:luck::luck:
with regards
:sekhon:
india🙂🙂
 
A heart block is a disease in the electrical system of the heart. This is opposed to coronary artery disease, which is disease of the blood vessels of the heart. While coronary artery disease can cause angina (chest pain) or myocardial infarction (heart attack), heart block can cause lightheadedness, syncope (fainting), and palpitations.

A heart block can be a blockage at any level of the electrical conduction system of the heart.

  • Blocks that occur within the sinoatrial node (SA node) are described as SA nodal blocks.
  • Blocks that occur within the atrioventricular node (AV node) are described as AV nodal blocks.
  • Blocks that occur below the AV node are known as infra-Hisian blocks (named after the bundle of His).
  • Blocks that occur within the left or right bundle branches are known as bundle branch blocks.
  • Blocks that occur within the fascicles of the left bundle branch are known as hemiblocks.👍

Types of SA nodal blocks include:🙂

  • SA node Wenckebach (Mobitz I)
  • SA node Mobitz II
  • SA node exit block

Types of AV nodal blocks

There are three basic types of AV nodal block:🙂



Types of infra-Hisian block

Infrahisian block describes block of the distal conduction system. Types of infrahisian block include:

:luck::luck:Of these types of infrahisian block, Mobitz II heart block is considered most important because of the possible progression to complete heart block.:luck::luck:


..................................


quote..

First-degree AV block, or PR prolongation, in which the PR interval is lengthened beyond 0.20 seconds.
Second-degree AV block refers to a conduction block between the atria and ventricles. There are two distinct types of second-degree AV block, called Type 1 and Type 2. In both types, a P wave is blocked; but, in Type 1, there are increasing delays in each cycle before the omission, whereas, in Type 2, there is no such pattern.
Type 2 Second-degree AV block, also known as Mobitz II is almost always a disease of the distal conduction system (His-Purkinje System).
Third-degree AV block, also known as complete heart block, is a medical condition in which the impulse generated in the SA node in the atrium does not propagate to the ventricles.
  • The P waves with a regular P to P interval represents the first rhythm.
  • The QRS complexes with a regular R to R interval represent the second rhythm. The PR interval will be variable, as the hallmark of complete heart block is no apparent relationship between P waves and QRS complexes.👍👍
 
impmostfibresascendingt.jpg


isnt it medial lemniscus?? i mean most of the ascending and descending tracts cross over in medial lemniscus????


confused.. pl someone explain....
medial lemniscus carries sensory information from the gracile and cuneate nucleus to the thalamus......mainly


The internal capsule contains both ascending and descending axons.

ans is internal capsule only
 
absorptionofcalciumfrom.jpg


y cant 5 be the answer?? parathyroid increases the calcium aborption from intestine..

the answer given is 4 in the answer key... confused...

The three major regulators of blood calcium are parathyroid hormone (PTH), vitamin D , and calcitonin.

PTH is normally released by the four parathyroid glands in the neck in response to low calcium levels in the bloodstream (hypocalcemia). PTH acts in three main ways:
(1) It causes the gastrointestinal tract to increase calcium absorption from food,It enhances the absorption of calcium in the intestine by increasing the production of activated vitamin D.....


(2) it causes the bones to release some of their calcium stores, and
(3) it causes the kidneys to excrete more phosphorous, which indirectly raises calcium levels.

Intestinal pH also affects calcium absorption—absorption is optimal with normal stomach acidity generated at meal times. Thus, persons with reduced stomach acidity (e.g., elderly persons, or persons on acid-reducing medicines) do not absorb calcium as well as others do.


SOOOOOOOO
4>>>>>5
ANS MUST B 4

 
The three major regulators of blood calcium are parathyroid hormone (PTH), vitamin D , and calcitonin.

PTH is normally released by the four parathyroid glands in the neck in response to low calcium levels in the bloodstream (hypocalcemia). PTH acts in three main ways:
(1) It causes the gastrointestinal tract to increase calcium absorption from food,It enhances the absorption of calcium in the intestine by increasing the production of activated vitamin D.....


(2) it causes the bones to release some of their calcium stores, and
(3) it causes the kidneys to excrete more phosphorous, which indirectly raises calcium levels.

Intestinal pH also affects calcium absorption—absorption is optimal with normal stomach acidity generated at meal times. Thus, persons with reduced stomach acidity (e.g., elderly persons, or persons on acid-reducing medicines) do not absorb calcium as well as others do.


SOOOOOOOO
4>>>>>5
ANS MUST B 4




how did u concluded 4>>>>>>>>5?? and answer to be 4?? i mean its clearly asked in the question , INCREASING calcium level ...not decreasing.. so think about it once more buddy...


and buddy can u plz elaborate more on ur last answer about why internal capsule and why not medial lemniscus?? i did not understood it properly...😀😀


hey thanks dphvj.. for the answers... i appreciate it...

here is my next doubt...
impsubliminalfringeofam.jpg


can anyone explain me what is subliminal fringe and what are these 4 options??

and hows the answer selected is correct??

👍
 
theanticodonontransferr.jpg
<<<<<---------- straight way ACG = UGC
rnadna.jpg


why in the 2nd question... we have to inverese the AA ...?? where as in the 1st que we dont have to???

i mean 5' ACG 3' === 5'UGC3' cannot be?? why is it B answer and not the E?????

i know i am just making silly mistakes.. but if anyone can clarify than it will be better.. i mean i wanna know exactly hows the base pair are changed.....

pl help me out..
 
theanticodonontransferr.jpg
<<<<<---------- straight way acg = ugc
rnadna.jpg


why in the 2nd question... We have to inverese the aa ...?? Where as in the 1st que we dont have to???

I mean 5' acg 3' === 5'ugc3' cannot be?? Why is it b answer and not the e?????

I know i am just making silly mistakes.. But if anyone can clarify than it will be better.. I mean i wanna know exactly hows the base pair are changed.....

Pl help me out..

a becomes u........ As: T : Is nt in rna its in dna only
c becomes g......[vice versa]
3 becomes 5 [vice versa]
sooooooo '

5 acg 3 .becomes......3 ugc 5

according to option.......its not there
so read it from back
5 cgu 3.....hoe dis help😉
 
how did u concluded 4>>>>>>>>5?? and answer to be 4?? i mean its clearly asked in the question , INCREASING calcium level ...not decreasing.. so think about it once more buddy...


and buddy can u plz elaborate more on ur last answer about why internal capsule and why not medial lemniscus?? i did not understood it properly...😀😀
INCREASE OF CA ABSORPTION DIRECTLY RELATED TO OPTION 4 AS COMPARED TO 5 ........SIMPLE DEAR😀
internal capsule and why not medial lemniscus??

ITS DIRECTLY GIVEN IN BASIC ANATOMY TEXT BOOKS DEAR....:idea:
 
INCREASE OF CA ABSORPTION DIRECTLY RELATED TO OPTION 4 AS COMPARED TO 5 ........SIMPLE DEAR😀
internal capsule and why not medial lemniscus??

ITS DIRECTLY GIVEN IN BASIC ANATOMY TEXT BOOKS DEAR....:idea:


😀😀😀 thanks... buddy..

prolongedvitaminadefeci.jpg


why 2 cannot be possible reason..?? does vit A defeciency cause enamel hypoplasia???

i just want to know one thing about fluoride.. if its less or not present in water does it cause hypoplaisa or any defeciency disorder?? or just tht caries prevalence becomes higher??
 
😀😀😀 thanks... buddy..

prolongedvitaminadefeci.jpg


why 2 cannot be possible reason..?? does vit A defeciency cause enamel hypoplasia???

i just want to know one thing about fluoride.. if its less or not present in water does it cause hypoplaisa or any defeciency disorder?? or just tht caries prevalence becomes higher??

hmmmm....fluoride makes the enamel LESS SOLUBLE......thts how it prevents caries.....
vitamins A,C nd D linked wid hypoplasia.........

since the question asks which is the LEAST imp.. hence the answer
 
here is my next doubt...
impsubliminalfringeofam.jpg


can anyone explain me what is subliminal fringe and what are these 4 options??

and hows the answer selected is correct??

👍

ppl i did not got any answer till now... can anyone tell me some info about the above quoted answer???


hmmmm....fluoride makes the enamel LESS SOLUBLE......thts how it prevents caries.....
vitamins A,C nd D linked wid hypoplasia.........

since the question asks which is the LEAST imp.. hence the answer


thanks lord velmont...
 
Thats the ans for sure. The explanation is i think because pancreas has an endocrine component also. so it does not need ducts to secrete.
Dontist don't panic. Read the Q's properly. We can make a lot of mistakes by not reading the Q properly.

 
Thats the ans for sure. The explanation is i think because pancreas has an endocrine component also. so it does not need ducts to secrete.
Dontist don't panic. Read the Q's properly. We can make a lot of mistakes by not reading the Q properly.


well thanks colors.. but i had read the question multiple times.. the thing is after re establishment of circulation y parotid gland wont function???

i mean circulation is established?? reason behind is just because it wont be innervated??

and did u point on answer tht pancreas will be functioning???
i have little more anxiety the reason behind is.. just 20 days left and i am yet to do with this physio biochem papers.. so worried.. 🙂 hope things go well..


i want to revise once more decks also once this gets over.. but revising decks wont take much time as like papers we get good questions to use our brain and solve.. taking more time... i am just able to solve one question paper per day.. so just worried.. i know i am tooo slow.. for just one paper.. that too just 1 subject thts just 100 questions.. lol but i read things and save the snapshots so tht it will be easy for me later to just overlook questions where i made the mistake.. 🙂so takes time...
 
Last edited:
Can you pls help me with this

assuming that P50=26 torts, under condition where pO2=30 torrs, the average number of O, molecules bound per hemoglobin molecule is closest to:
a. 0.5
b. Less than 1
c. Almost 2
d. Greater than 2
e. Greater than 3
 
well thanks colors.. but i had read the question multiple times.. the thing is after re establishment of circulation y parotid gland wont function???

i mean circulation is established?? reason behind is just because it wont be innervated??

and did u point on answer tht pancreas will be functioning???
i have little more anxiety the reason behind is.. just 20 days left and i am yet to do with this physio biochem papers.. so worried.. 🙂 hope things go well..


i want to revise once more decks also once this gets over.. but revising decks wont take much time as like papers we get good questions to use our brain and solve.. taking more time... i am just able to solve one question paper per day.. so just worried.. i know i am tooo slow.. for just one paper.. that too just 1 subject thts just 100 questions.. lol but i read things and save the snapshots so tht it will be easy for me later to just overlook questions where i made the mistake.. 🙂so takes time...
PANCREASE IN BOTH ENDO AND EXOCRINE GLAND
parotid need nerve supply to work at abbarent site...as in frey syndrome

but still cant reach the ans ........
😀😀
 
ironporphyrinprotienstr.jpg


isnt it hemoglobin?? why cytochromes???
. Some iron-containing porphyrins are called hemes; and heme-containing proteins, or hemoproteins, are found extensively in Nature. Hemoglobin and myoglobin are two O2-binding proteins that contain iron porphyrins.
👍
Any protein containing iron and porphyrin; examples are hemoglobin, the cytochromes, and catalase.

answer is among 2 and 5 😕
 
PANCREASE IN BOTH ENDO AND EXOCRINE GLAND
parotid need nerve supply to work at abbarent site...as in frey syndrome

but still cant reach the ans ........
😀😀

😀😀😀

. Some iron-containing porphyrins are called hemes; and heme-containing proteins, or hemoproteins, are found extensively in Nature. Hemoglobin and myoglobin are two O2-binding proteins that contain iron porphyrins.
👍
Any protein containing iron and porphyrin; examples are hemoglobin, the cytochromes, and catalase.

answer is among 2 and 5 😕

2 and 5 or 4?? :idea::idea:
 
if2vesselsareconnectedi.jpg


the only thin this reminds me is of 12th grade physics.. series and parallel circuits lol....

but does anyone knows the concept behind this ??? lol
 
if2vesselsareconnectedi.jpg


the only thin this reminds me is of 12th grade physics.. series and parallel circuits lol....

but does anyone knows the concept behind this ??? lol

they ask stuff like wat happens when a kidney is removed..in relation to cardiac output......
ALWAYS rmr....
kidneys r in series circuit..if u remove 1 kidney.......cardiac output increases.....

opposite fer parallel circuits......
i know its confusing.......nd a lil difficult to believe...but well....thts the funda behind it:idea:
 
ok so kidney is in series connection if u remove one than CO will icnrease..

can u tell me which organs are in parallel?? and btw where is this thing given?? i mean i am not able to get anywhere about it... it will be great if u can tell me so tht i can refer little more...

one more thing is about whats the corellation with resistance?? i mean in series and parallel connection???

u have told about the relation of CO and series and parallel connection.. can u just make similar statement of relation of series and parallel connection and its relation to resistance??

i am gettin some direction to think but i need to conform from ur side also...

thanks lord...🙂
 
ok so kidney is in series connection if u remove one than CO will icnrease..

can u tell me which organs are in parallel?? and btw where is this thing given?? i mean i am not able to get anywhere about it... it will be great if u can tell me so tht i can refer little more...

one more thing is about whats the corellation with resistance?? i mean in series and parallel connection???

u have told about the relation of CO and series and parallel connection.. can u just make similar statement of relation of series and parallel connection and its relation to resistance??

i am gettin some direction to think but i need to conform from ur side also...

thanks lord...🙂


its given in USMLE videos..if u have access to those...tk a peek.might help ya....👍
 
whats the corellation with resistance?? i mean in series and parallel connection???

hey lord i do have all of those videos.. which lecture u r pointing this thing??

sorry if i am being too picky 🙂 well if u just remeber or know it than tell me which video .. i will go thrru...

and thanks a lot for the info...

u guys rock....
 
whats the corellation with resistance?? i mean in series and parallel connection???

hey lord i do have all of those videos.. which lecture u r pointing this thing??

sorry if i am being too picky 🙂 well if u just remeber or know it than tell me which video .. i will go thrru...

and thanks a lot for the info...

u guys rock....

hey....
check in the renal physio section in those videos......i don rmr exactly....but its not in regional transport..its in the very basic one.....guess the first or the 2nd in tht section..
 
Can you pls help me with this

assuming that P50=26 torts, under condition where pO2=30 torrs, the average number of O, molecules bound per hemoglobin molecule is closest to:
a. 0.5
b. Less than 1
c. Almost 2
d. Greater than 2
e. Greater than 3

Answer is d
P50 means a pressure at which half of the oxygen atoms will be saturated in a hemoglobin. Since 1 hb can cobine with 4 oxygen atoms so at 26 torr it will be exactly 2. Since pressure given is slightly greater than 26 answer is greater than 2.

Hope it helps!!!🙂
 
diffusionisleastimporta.jpg


most of the glomerular filtration is done by diffusion m i correct???
the question is about LEAST important than how can 1 be the answer

i think ans can be 2. as like Na through a nerve membrane is by soduim potassium pump... where there is no diffusion...

anybody have idea?? correct me if wrong...
 
velocityofnerveimpulsec.jpg


why not myelin sheath?? i mean if isnt the myelin sheath plays role in conduction of nerve impulse?? in unmyelinated nerve fibres its slow and in myelinated its fast ..???

why cant 2 be the possible answer??

thanks

help appreciated.
 
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