joonkimdds

Senior Member
10+ Year Member
7+ Year Member
Jun 30, 2005
2,780
2
Status
Pre-Dental
I believe that LiAlH4 can change
aldehyde, COOH, ester into primary alcohol and
ketone into 2ndary alcohol.

Beside these, I don't understand what else it does.

In roadmap2, there are two reactions that have LiAlH4 and they are none of what I wrote above.

First one is...
a ring-CH2N3 and the product is a ring-CH2-NH2.
(I don't even know how N3 exist. is it CH2-N-N-N?)

second one is
a ring-NH-COCH3 and the product is a ring-NH-CH2-CH3.
 

Danny289

Member
10+ Year Member
Dec 2, 2006
1,523
4
Status
Pre-Dental
I believe that LiAlH4 can change
aldehyde, COOH, ester into primary alcohol and
ketone into 2ndary alcohol.

Beside these, I don't understand what else it does.

In roadmap2, there are two reactions that have LiAlH4 and they are none of what I wrote above.

First one is...
a ring-CH2N3 and the product is a ring-CH2-NH2.
(I don't even know how N3 exist. is it CH2-N-N-N?)

second one is
a ring-NH-COCH3 and the product is a ring-NH-CH2-CH3.
LiAlH4 is reduction agent, ask yourself what is the meaning of reduction? It means gaining "H" or loosing "O"( I don't go for gaining electron here) then you will find out what is going on.
 
About the Ads

joonkimdds

Senior Member
10+ Year Member
7+ Year Member
Jun 30, 2005
2,780
2
Status
Pre-Dental
Hopefully this helps: http://upload.wikimedia.org/wikipedia/commons/3/30/LAH_rxns.png
The N3 thing might be a typo. I've never seen that either. An N2 group is called a diazonium if I recall correctly...
For the second example I'm pretty sure and ester would be reduced to an alcohol. That's what it shows on that link I put above at least...
Thanks for the link :)
by the way N3 is not a typo because your link shows it too :D
So I guess I can just memorize N3 from your link.

But I am still not sure what the 2nd example is.
it's not in the link either.
 

zuma35

10+ Year Member
5+ Year Member
Sep 6, 2008
128
0
Status
Dental Student
Specifically for an amide, LAH reduces the carbonyl to a CH2.
 

IdahoDoc

10+ Year Member
7+ Year Member
Aug 26, 2007
500
1
Status
Dental Student
The N3 is drawn out like this

N=N=N and there are charges obviously it is really only used to then be reduced to N=N and i believe it it is done with LiAlH4 in ET2O.
 
About the Ads