I highly recommend getting your application in prior to starting the MS program (unless you need extra LORs). I submitted my application maybe a week or two after MGA started and I waited until then so that my advisor could go over my application. Whether you're AS or BP, you'll have a chance to meet with your advisor and go over your application at the beginning of the semester. All my LORs were from previous employees/physicians/undergrad professors, however, if you need a LOR from a professor in the Masters program, then you'll have to wait, spend some time forming those relationships, and then ask them before the deadline (which I believe was like November/December for us?). But that being said, stay on top of your LORs. In my year, I had my classmates who waited up until the deadline and were freaking out about getting their application in in the midst of finals, etc. Better to solely focus on your classes if you get most of your application out of the way before you get here. OH, and make sure you have a physician letter, preferably DO. If you don't, start looking at options on how to acquire one, whether that means finding a physician to shadow nearby or in Knox or hitting up someone from your past. As for how to approach our professors here for LORs - our professors are chill and nice, so if you go to office hours, participate in class, ask questions, I highly doubt they'll turn you down for a LOR (unless they have some specific criteria you have to meet). I'm sure
@surgeryDO can add to what I said above.