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pgg, what about Marinol (dronabinol)? When I was a med. student in peds, I saw one of the residents write for this for a cancer patient. I believe it comes PO. It is a derivative of marijuana. It seemed to help a little, but wasn't as dramatic as I expected.
http://www.justice.gov/dea/ongoing/marinol.html
Advocates for medical marijuana have various arguments for why Marinol is inferior to smoking a joint; some of them are even plausible. Mainly they seem to say that while Marinol is just one compound (synthetic THC), different strains of the plant presumably have other cannabinoids and maybe other active ingredients. It could be that they prefer smoking it for the same reason people smoke crack instead of taking it PO: very rapid, titratable effect. There's powerful psychiatric feedback involved in smoking a drug.
Street drugs make people feel good, and even sick people can feel better when using them. That doesn't mean the FDA should approve those drugs as prescription medications for the treatment of medical conditions.
There's a world of difference between giving a patient a morphine PCA and an opium pipe. Wildy variable potency, unregulated quality control, impurities, inconsistent/user-dependent dosing mechanisms - not to mention the proven HARMFUL effects of smoking anything - this is the stuff of quacks and snake-oil salesmen, not modern medicine.