What type of pre-reqs do you need to take? Are they classes that the program required or suggested or things you just think you need to know? I am probably taking a calculus class my first semester so I am better prepared for my second semester of biostats if I end up selecting a program that requires 2 semesters of biostats. 2 out of the 3 programs I am considering have the 2 semester requirement regardless of your concentration. However, this wasn't a requirement or a suggestion. I just want to do well in the classes and strengthen my quantitative skills. I do worry about the courseload since undergrad math classes usually involve daily homework assignments. I am going to talk to my advisor about it once I decide where I am going. I think if the school is requiring you take classes, then your advisor should be able to help you figure out what is reasonable, etc.