this combination is really high on the DEA's radar, and also the radar of some payer's organizations. You really want to do your due diligence (contacting all prescribers, if they differ, and checking PMPs, plus ensuring there is a legitimate patient-provider relationship) if you see this combo as you can likely get the pants sued off you if there really isn't a great reason for it.
http://www.wci360.com/news/article/deadly-drug-combinations-escaping-notice-a-healthesystems-report
Also check out the NABP's "Red Flags" video. It's cheesy, but maybe helpful:
I don't think this is fair at all. Prescribers know it is a dangerous combination but by prescribing them together, they must know the benefits outweigh the risk. I believe my job is to counsel the patient, not to get the prescribers to change the . combination.
What is your opinion?