Does anyone have a cheat sheet for risks vs benefits and indications vs contraindications for the various forms of labor induction?
May not be up to date. I don't practice OB anymore.
Indications for Induction (modified for the outpatient setting):1
Fetal demise
Gestational hypertension
SBP >140, DBP >90 associated with proteinuria ( ≥0.3 g/24 hrs)
HELLP syndrome
Eclampsia
PROM
Fetal compromise
BPP <6/10
Severe or asymmetric IUGR
Postterm pregnancy (>41 weeks gestation) [Note this is not ≥41 weeks gestation]
Situations for which induction may be considered :2
Fetal macrosomia (Infant >4500 grams by ultrasound)
Gestational diabetes >40 weeks gestation
Other conditions on a case-by-case basis
Criteria to be met prior to induction :
Accurate assessment of gestational age
FHT by Doppler for ≥30 weeks
Positive hCG for ≥36 weeks
CRL supporting a gestational age of ≥39 weeks
13-20 week US confirming a clinical gestational age of ≥39 weeks
Estimation of fetal weight
Assessment of fetal presentation
Calculation of Bishop score
If <6, induction should be preceded by cervical ripening
Discussion with patient of risks (vs. benefits) of induction
Uterine tachysystole
Hyperstimulation syndrome
Fetal heart rate decelerations
Uterine atony
Placental abruption
Uterine rupture
Documentation of indication for induction and discussion of risks/benefits
Acceptable ripening agents :
Balloon device (Foley)
Extra-amniotic saline infusion
Hygroscopic dilators
Prostaglandin E2 (Cervidil, Prostin, dinoprostone, or Prepidil)
Misoprostol
Acceptable induction agents :
Oxytocin
Misoprostol
Notes:
These may be considered on a case-by-case basis, but also need to be discussed with the faculty on call at the beginning of the induction (i.e., placement of ripening agent or admission for pitocin) for the date under consideration, as there may be differences in practice.
References:
Induction of Labor. ACOG Technical Bulletin #10. November, 1999.
Fetal Macrosomia. ACOG Technical Bulletin #22. November, 2000.
Gestational Diabetes. ACOG Technical Bulletin #30. September, 2001.
Kelly, AJ. Kavanagh, J. Thomas, J. Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term. [Systematic Review] Cochrane Pregnancy and Childbirth Group Cochrane Database of Systematic Reviews. 2, 2006.
Hofmeyr, GJ. Gulmezoglu, AM. Vaginal misoprostol for cervical ripening and induction of labour. [Systematic Review] Cochrane Pregnancy and Childbirth Group Cochrane Database of Systematic Reviews. 2, 2006.
Irion, O. Boulvain, M. Induction of labour for suspected fetal macrosomia. [Systematic Review] Cochrane Pregnancy and Childbirth Group Cochrane Database of Systematic Reviews. 2, 2006.
Boulvain, M. Stan, C. Irion, O. Elective delivery in diabetic pregnant women. [Systematic Review] Cochrane Pregnancy and Childbirth Group Cochrane Database of Systematic Reviews. 2, 2006.
Howarth, GR. Botha, DJ. Amniotomy plus intravenous oxytocin for induction of labour. [Systematic Review] Cochrane Pregnancy and Childbirth Group Cochrane Database of Systematic Reviews. 2, 2006.
Bricker, L. Luckas, M. Amniotomy alone for induction of labour. [Systematic Review] Cochrane Pregnancy and Childbirth Group Cochrane Database of Systematic Reviews. 2, 2006.
Crowley, P. Interventions for preventing or improving the outcome of delivery at or beyond term. [Systematic Review] Cochrane Pregnancy and Childbirth Group Cochrane Database of Systematic Reviews. 2, 2006.
Tenore J. Methods for cervical ripening and induction of labor. Am Fam Physician 2003;67(10):2076, 2078, 2083-4.
Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 2000;183(1):S1-S22.
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