Oxygen content during excercise

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How does O2 content in arteries/veins differ from one side of a body to another during exercise. For example, if I'm lifting weights with my right arm only, will artery/vein O2 blood concentration in my right arm differ from my left arm?

 

[N1st]

Yes, more O2 is used and more CO2 is produced when a muscle is being used than when it is not.