It's the hardest thing I have ever done--can't lie to you--take your PA didactic experience and triple it, easy. Nothing is off the table in terms of pathophys, Biochem, genetics, histology, anatomy, molecular bio of pharm...for example, today's clinical neurology exam covered 38 hr of lecture over about 6 lecture days. Imagine everything you need to know about CNS tumors, infections, developmental/congenital anomalies of CNS, movement disorders, dementia, migraine & other HA, stroke/ischemia, MS and less common demyelination disorders, and a few others I can't recall cuz my brain is fried. And we're not talking PA school exams that are high-yield what's-gonna-be-on-PANCE, but every little enzyme and quirky histopath finding you didn't learn because it really isn't important for clinicians
Perhaps if you are closer to the average age of medical students you won't find it as hard to adjust to being a student again like me. I spent the greater part of first semester (core) and part of 2nd retraining my brain to STOP thinking like a PA and start thinking like a PhD lol....
Now that we're into systems it's a beautiful thing that I get to think like a clinician again, but I still have to keep my mind open to "what are the PhDs gonna ask me about this disorder?" when studying. It is an adjustment for sure.
There are 7 of us in the LECOM APAP experiment. I happen to be the only woman and at the upper end of experience as a PA (one guy is older than me and has about 14 yr I think, I have 12). We are all hanging in there. I think the 3 PBL guys are doing fantastic. One of our smart cookies is a DSPer and at the top. I tried DSP, couldn't do it. WAY too stressful. I went back to lecture in January and it was a wise move for me. I probably should have been PBL but I chickened out. Doesn't matter ultimately as I just want to do well on boards and graduate and match for residency
My best advice to you? If you are in PA school now, finish it. Learn as much as you can and READ EVERY DAY. Work for at least a year, or a few. Be SURE you really want to do this to your financial life and personal life. Make money but save it--don't get too used to spending and enjoying the fruits of your labor
that's the 2nd hardest part of going back to school--giving up a 6-figure income to take on more debt and earn nothing for a minimum of six years!
Good luck
Lisa