Please explain the difference between O2 Content and Concentraion

[dentbaby]

Hi,
Please explain the difference between Oxygen content and concentration.I am really confused with this topic.Is Oxygen concentration in blood and oxygen content the same??
Then is O2 present in blood is diffrent from dissoled in plasma???
Thanks in advance

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[Huggies]

.Partial pressure of Oxygen [..pO..2..].

• .Normal 80 - 104 mmHg.
• .Direct measure; partial pressure of oxygen in blood.
• .Reflects amount of oxygen dissolved in plasma.
• .Gives an indication of adequacy of respiratory ventilation & diffusion especially reflecting the quantity of oxygen diffusing from the alveoli into the pulmonary capillaries.
• .Note that a normal pO..2.. may not necessarily mean adequate O..2.. delivery to the cells if the Hb is reduced or defective.
• .Depressions in O2 are commonly associated with degeneration of the respiratory membranes or ventilation-perfusion imbalances.
• .Lower in newborn (40-60); elderly (80 - 1 for every year over 60).

.Arterial oxygen saturation [..SaO..2..].

• .Normally >94% saturated.
• .A measure of the percentage of O..2.. combined with Hb to the total amount of O..2..with which Hb could combine.
• .Plotted on oxygen haemoglobin dissociation curve or measured directly.
• .Is the extent to which haemoglobin is saturated with oxygen.
• .Note that 97% of oxygen transport is with Hb.
• .Influenced by temperature, pH, pCO2.

. So if I understand it correctly, oxygen content is one dissolved in blood and expressed in mmHg since it's a gas, and concentration is in terms of how much is bound to Hb, but perhaps someone else can add to this.
.

 

[goyalD141284]

huggies..

u explained it well

so in simpler terms,

dissolved Oxygen in plasma produces partial pressure of O2, i.e PO2,
and it is this partial pressure (PO2) which keeps O2 bound to Hb.

 

[preciousdentist]

so partial pressure of oxygen (dissolved oxygen in plasma) is indicating its content??

and concentration is indicated by oxygen saturation on haemoglobin??

 

[dr37]

O2 Content: Total amount of O2 carried in blood. determined by amt of Hb and its saturation

O2 Saturation: Amount of Hb saturated with O2. determined by PO2.

 

[aphistis]

O2 Content: Total amount of O2 carried in blood. determined by amt of Hb and its saturation

O2 Saturation: Amount of Hb saturated with O2. determined by PO2.

This is almost correct, but not quite.

Oxygen content (paO2) = Oxygen bound to hemoglobin + free oxygen dissolved in plasma. Measured in mmHg. Used to directly measure total amount of oxygen circulating in blood. Measurement requires invasively obtaining an arterial blood sample for gas analysis.

Oxygen saturation (saO2) = (oxyhemoglobin)/(total hemoglobin in blood) * 100%. Measured in percent. Ignores free oxygen dissolved in plasma. Used to determine amount of oxygen bound to hemoglobin, and serves as an effective proxy for determining oxygenation status (because as someone else noted, nearly 100% of plasma oxygen is bound to hemoglobin). Can be used to approximate paO2 via paO2/saO2 hemoglobin dissociation curve. Can be easily and non-invasively measured in real time using a finger/ear/nose/lip probe.

Hope this helps.