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Suppose that you expose a human cell line to a functionalized gold nanoparticle. Adsorbed onto the particle are ligands of one of two varieties, hexyl and methyl.
Hexyl particles are very toxic to the cell, but cause little DNA damage.
Methyl particles are far less toxic to the cell, but cause immense DNA damage.
How can this be so? What mechanisms may be at work (Reactive Oxidant Species - ROS)?
(Disclaimer: This is NOT homework!)
Hexyl particles are very toxic to the cell, but cause little DNA damage.
Methyl particles are far less toxic to the cell, but cause immense DNA damage.
How can this be so? What mechanisms may be at work (Reactive Oxidant Species - ROS)?
(Disclaimer: This is NOT homework!)