question

[BlackPuma]

Advertisement - Members don't see this ad

vimentin is a marker of what? it says mesenchymal, but the answer choices were adenocarinoma, fibro something, prostate, melanoma, and something else...does anyoene know

 

[Olanzapine]

probably the fibro-something, with the something standing for sarcoma. Googling will get you far in medicine.
http://www.biogenex.net/antibody.php?show=000279

 

[Blade28]

I agree, use the web. A quick search on Yahoo! using the keyword "vimentin" reveals this as the first hit:

"Vimentin is of limited value as a diagnostic tool; however, when used in combination with other antibodies (in panels) it is useful for the subclassification of a given tumor. Expression of vimentin, when used in conjunction with keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas."

(from http://www.cellmarque.com/2000/Pages/catalog/vim.html)

 

[BlackPuma]

I agree, use the web. A quick search on Yahoo! using the keyword "vimentin" reveals this as the first hit:

"Vimentin is of limited value as a diagnostic tool; however, when used in combination with other antibodies (in panels) it is useful for the subclassification of a given tumor. Expression of vimentin, when used in conjunction with keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas."

(from http://www.cellmarque.com/2000/Pages/catalog/vim.html)

no I disagree with using the web, when I did a search on it, I got all kinds of responses..

the best marker for melanoma is S-100, and the question had Vimentin alone not with keratin......so I don't think melanoma was the answer....although now that I think of it...lymphoma might have been one of the options...

hmmm....vimentin wasn't in BRS...but a couple of sources mentioned it is a marker for mesenchmyal origin...