Regarding acetylcholine

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grimmymac

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I had a question on a practice exam:

What will happen to functioning acetylcholines at the end of their neural-signal transmission?

My answer: They will be absorbed by axon bearing the pre-synaptic membrane and are ready to be reused

Test solution: They will immediately be broken down by acetylcholinesterases at the synaptic cleft.

From what I understand, acetylcholine can do both. Am I wrong somewhere?

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-Acetylcholinesterase is an enzyme that's always present in the synaptic cleft. It breaks down acetylcholine soon after acetylcholine is released from the synaptic terminal. This breakdown is the primary mechanism for clearing acetylcholine from the synaptic cleft.

Hope this helps

Good luck in your studies and on the DAT

Nancy
 
Acetylcholine is broken down into choline and acetic acid by the enzyme acetylcholine esterase, after which one of these products, choline is transported back into the axon for further signal transmission.
 
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