Unfortunately all of the interviewees are different. Be prepared for these kinds of questions: Why Sackler: rather than a US school; rather than BGU or Technion? Any Israel experience? If not, do you know you can handle it? Are your parents supportive? How's your Hebrew? I'm a firm believer that even if you've just started learning and only know a few words, the fact that you're doing so puts you in a favorable light. Knowing any Sackler grads or anything about the school is also a good thing. A Sackler grad shooting the committee an email on your behalf does wonders. I believe that is why I'm in.
Of course you need to be able to answer all the usual med school questions: why medicine, etc. Also, since the interview is "Open File," be able to answer questions related to your application.
If you don't mind me asking, where are you interviewing?