Married with two kids...one of them a special needs child, though high functioning. Wife got undergrad and teaching degree and now finishing up her masters. She has a couple one week classes that will overlap my first year. I supported her through it and every time she felt guilty and wanted to stop and get a regular job, I just said "don't give up on your dream......" At that point I had no idea I was going to medical school.
We talk about it almost daily. I think I am more worried than she is. I just don't want things to get too out of whack. We have made it through some rough times, as most marriages endure, so I am confident, but worried.
I think the most important thing is that you prioritize your time......school then family though that order may have to change some days depending on how big the first is.....the other things like social time, free time and sleep will suffer.