TBR Reproduction Passage

[premedicine555]

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Two questions:


1) I'm confused with the antigen/antibody wording. When it says "anti-hCG antibody" does that mean the antibody attacks ("bonds with") hCG?

Also, similar question: If H-Y antigen promotes testicular formation, then does anti-HY antigen not form anything?
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2) Passage VIII, page 245:
Background info: a vaccine promotes antibodies against hormone hCG, made by embryo. non-pregnant levels according to the passage is 0mol/l for hCG.
QUESTIOn: How would this anti-HCG vaccine affect a woman's normal menstrual cycle?

My choice: Although it would raise hCG levels to pregnancy levels, it would allow normal menstration.

Answer: The vaccine would NOT change normal menstrual cycles

I thought that whenever hCG levels would increase past 0 mol/L, then it's considered concentrations that are towards pregnancy levels since it acts as a contraceptive. The answers says "hCG levels will be reduced to nonpregnant levels - 0 mol/L" but the passage does not mention it at all.. I know it decreases after a while since antibody level from vaccine decreases, but aghh still confused..

 

[brandonh4]

Two questions:


1) I'm confused with the antigen/antibody wording. When it says "anti-hCG antibody" does that mean the antibody attacks ("bonds with") hCG?

Also, similar question: If H-Y antigen promotes testicular formation, then does anti-HY antigen not form anything?
--------------------------------------------------------------------------------------------------------------------------------
2) Passage VIII, page 245:
Background info: a vaccine promotes antibodies against hormone hCG, made by embryo. non-pregnant levels according to the passage is 0mol/l for hCG.
QUESTIOn: How would this anti-HCG vaccine affect a woman's normal menstrual cycle?

My choice: Although it would raise hCG levels to pregnancy levels, it would allow normal menstration.

Answer: The vaccine would NOT change normal menstrual cycles

I thought that whenever hCG levels would increase past 0 mol/L, then it's considered concentrations that are towards pregnancy levels since it acts as a contraceptive. The answers says "hCG levels will be reduced to nonpregnant levels - 0 mol/L" but the passage does not mention it at all.. I know it decreases after a while since antibody level from vaccine decreases, but aghh still confused..

Yes, an anti-X antibody means that the antibody is specific for X.

And I'm not sure what the confusion is for the second part. The antibodies attack any existing hCG, so that pregnancy cannot progress. Therefore, there would be no free hCG to detect.

 

[MedPR]

Two questions:


1) I'm confused with the antigen/antibody wording. When it says "anti-hCG antibody" does that mean the antibody attacks ("bonds with") hCG?

Also, similar question: If H-Y antigen promotes testicular formation, then does anti-HY antigen not form anything?
--------------------------------------------------------------------------------------------------------------------------------
2) Passage VIII, page 245:
Background info: a vaccine promotes antibodies against hormone hCG, made by embryo. non-pregnant levels according to the passage is 0mol/l for hCG.
QUESTIOn: How would this anti-HCG vaccine affect a woman's normal menstrual cycle?

My choice: Although it would raise hCG levels to pregnancy levels, it would allow normal menstration.

Answer: The vaccine would NOT change normal menstrual cycles

I thought that whenever hCG levels would increase past 0 mol/L, then it's considered concentrations that are towards pregnancy levels since it acts as a contraceptive. The answers says "hCG levels will be reduced to nonpregnant levels - 0 mol/L" but the passage does not mention it at all.. I know it decreases after a while since antibody level from vaccine decreases, but aghh still confused..

Yes, anti-hcg antibody will recognize hcg as an antigen.

if H-Y antigen promotes testicular formation, anti H-Y antibody will prevent testicular formation by inhibiting H-Y antigen.

hCG is not present during menstruation, it is only secreted during pregnancy. No pregnancy = no hCG. If it helps you understand, a vaccine with anti-hCG antibody would terminate all pregnancies because it would destroy hCG in pregnant women.

 

[premedicine555]

Thank you MedPR and brandon, makes sense now (antibody "traps" the hCG so body can no longer mimic pregnancy).

Also, in regard to the same passage, "anti-X ANTIGEN" mean the opposite effect of antigen-X (ie: HY antigen promotes testicular organogenesis; but anti-HY ANTIGEN does not). This was in passage VII.

 

[MedPR]

Thank you MedPR and brandon, makes sense now (antibody "traps" the hCG so body can no longer mimic pregnancy).

Also, in regard to the same passage, "anti-X ANTIGEN" mean the opposite effect of antigen-X (ie: HY antigen promotes testicular organogenesis; but anti-HY ANTIGEN does not). This was in passage VII.

The body doesn't mimic pregnancy. The question is testing whether or not you know that hCG is present only in pregnancy and not in normal menstruation. The reason the antibody vaccine doesn't affect the normal cycle is that hCG does not play a role in the normal cycle.

Do you mean "anti-X antibody"? Antibodies don't have "opposite effects of antigens". They simply mark the antigen for destruction making the antigen useless. In other words, insulin and glucagon have opposite effects on serum glucose levels, but glucagon is not an "anti-insulin antibody" If Glucagon and insulin might have feedback effects on each other if they come in contact, but glucagon does not act as an antibody against insulin.

 

[premedicine555]

Nope, I mean "anti-X antigen". The answer to Q 48 specfically writes "anti-HY ANTIGEN" but I'm starting to think that they meant antibody.. so it would be a writing error.

 

[MedPR]

It says "anti-H-Y antigen anibody"

That means an antibody against H-Y antigen.

 

[premedicine555]

Oh yeah, for the question it says that, but for the ANSWER it just says "anti-HY antigen".

 

[MedPR]

Oh yeah, for the question it says that, but for the ANSWER it just says "anti-HY antigen".

Yea, probably an error then. I don't really want to look at the answers as I haven't done this passage yet 🙂

 

[premedicine555]

Yea, probably an error then. I don't really want to look at the answers as I haven't done this passage yet 🙂

Ah, got it. Thanks for your help, MedPR! you are awesome!