Hand written notes are best, if you're good at making them thoughtful and referring to some unique interaction you had during the interview woven in naturally, and you buy some really cute ones. HOWEVER, if you are given emails adresses you should use those instead. If you are told NOT to send any thank you's, that trumps it all.
You should always ask (not the interviewer directly) but whoever is your contact person for interview day what the thank you note policy is.
You should never disobey instructions given by the med school in your app process, one of the qualities they are looking for is following instructions, and it will automatically count against you to disobey.
They always say thank you notes don't mean much, probably true, but I've known of cases where they seemed to have a positive effect. They key is to know how to use them to your advantage and not **** yourself with them.
Email AND handwritten? Way too desperate.
Do what they say and use handwritten if given the choice.