I am from Michigan as well, and as far as I can tell, both Michigan and Wayne are excellent medical schools. Michigan has a better reputation though, so it is more likely that you will get a good residency placement anywhere around the country. Although this is also possible coming from Wayne, I think the majority of Wayne graduates stay in the state of Michigan, and a decent amount complete their residency at U of M. So basically, if you plan on staying in Michigan, they are equally good, but if you have plans to do your residency somewhere else, you may have a slight advantage if you go to Michigan. But, of course, what matters most for residency placement isn't the school you come from, its your board scores and letters of rec, so keep that in mind too!