Lets get scientific and think logically in this discussion now.
Cancer has been around every sense the days of the dinosaurs. If cancer was one disease (which we all here know its not), cancer would have been done away with a long time ago for as many millions and millions of dollars that has been spent for cancer research. What needs to be done, and I think its finally come to this stage, is researching cancer pathway by pathway. Therefore, treatments for cancers should be done on a pathway by pathway basis. There is a new cancer genome project going on (cant think of the correct name at the moment) to study the underlying mechanisms of cancer development.
Some forms of cancer can already be cured by a complete blood transfusion or by using hematopoietic stem cells. However, not all forms of cancer can be cured. This is due to some forms of cancer being caused by viruses and bacteria (i.e. breast cancer). Also, there will always be some forms of skin cancer around because of the social identity of being hot looking with a tan during the summer.
I dont study cancer that much, but from what I know, if p53 has a downregulator that becomes mutated it can lead to dysfunctional mechanisms of p53. As a result, when a cell becomes stressed by some environmental cause, cancer could possibly develop.
What is more important, as much as it sucks to hear it, is not really the cure for cancers, but for the ability to prolong the onset of disease and prolong the health of the individual. Should the prolonging health of a baby have more precedence then the prolonging the health of an elderly person?
When talking about catastrophic viral outbreaks, humans lack the ability currently to be on the same level understanding the evolution of viruses compared to how fast some RNA viruses can mutate. Take the yearly flu for example. We humans have yet been able to develop a vaccine that is able to do away the common cold. Yes scientists have the genome of many viruses and bacteria sequenced, but that is only the starting stage. Many decades of research has to take place to understand the function of the genes and the proteins. Then comes the time for vaccine development. By the time scientists can understand the function of a virus, the chances of the gene to have already evolved is there.
HIV is mutating at a rate where scientists are not able to develop a valuable vaccine fast enough to do away with HIV. Some drugs have been developed to prolong the time a person has AIDS, but not cured AIDS. What I fear is, if AIDS is cured some day we will see a huge population growth. Right now many people are afraid to have sexual intercourse with an unknown individual because of the fear of contracting HIV. If there becomes an over-the-counter drug a person can take to prevent the transmission of HIV, then more people will have sexual intercourse with strangers
possibly leading to more one night stand pregnancys. As it is right now, AIDS is the silent killer of many millions of people around the world.
The most efficient way to prevent passing on of genetic diseases is to have genetic screening done. Even with doing this, there will always be the chance of genetic diseases being passed on to new generations.
What is not understood with trinucleotide repeat neurodegenerative diseases is the unknown mechanisms of how and why the trinucleotide repeats continue to expand every generation.
I have always thought over the last few years is if we humans were to come to a point where we are able to prolong the onset of diseases that can last a persons whole life, then the population on this planet will swell to a point where our recourses will become obsolete. Therefore, humans will need to start exploring about living on different planets (i.e. the moon and Mars). When doing this there will be brought about new diseases and disorders that we have not yet encountered because of the different environmental pressures that will be put onto our genetic makeup and chemical reactions.
As we all know, we humans were once animal hunters and have now moved to where we sit on our buts all day long (for most jobs anyways). As a result, we have become a fatter species. Thus, leading to complex diseases like diabetes, some forms of cancer, inflammatory diseases, obesity, restless leg syndrome, etc. We have yet been able to adapt to our new life style as a whole species. I suspect by the time we humans have adjusted to our new life style, we will have already been started to force a change of our lifestyle again and brining on new problems.
When a vaccine has been able to cure a viral or bacterial disease, we already have experienced vaccines to not work with due time. Wasn't there a story a couple of months ago where the CDC said that some common infection in children will no longer be givin medication for? I think it deals with the ear but can't remember.
I have always believed the best way to fight diseases is to use our immune system and not bring in so many foreign substances.