##--DMU Class Of 2010--## part 02

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It'sElectric said:
I'm sitting here going through the anti-psychotics pharm lecture and his explanation of Slide 10 (in regards to binding affinity and dosage) makes absolutely no sense. In fact, it sounds like he's describing something opposite to what the graph actually says.

Did he explain it incorrectly, or would some care to explain what I'm missing?
Click to expand...

Hey, I just saw this now so, this is what I got out of it if it helps you:

X is dose, Y is binding affinity:

a more potent drug would have a HIGH affinity for a low dose (haloperidol) while a low potent drug would have a LOW affinity at a high dose (chlorprmazine).
 
I believe that I see what you're saying. I think it's basically the idea that the low potent drugs require a much higher dose to increase the binding affinity than the high potent drugs. The graph is just kind of misleading.
 
It'sElectric said:
I believe that I see what you're saying. I think it's basically the idea that the low potent drugs require a much higher dose to increase the binding affinity than the high potent drugs. The graph is just kind of misleading.
Click to expand...

You got it!
Just remember the two drugs at the extremes and you should be golden.
 
Jamers said:
Hey, I just saw this now so, this is what I got out of it if it helps you:

X is dose, Y is binding affinity:

a more potent drug would have a HIGH affinity for a low dose (haloperidol) while a low potent drug would have a LOW affinity at a high dose (chlorprmazine).
Click to expand...

More potent=high affinity AND HIGH SELECTIVITY for DA receptors and the inverse is true for low potent drugs. Just throwing in the whole SELECTIVITY in there for ya Jamers. Good to have you posting again on these boards, we missed you.
 
I Love Caffeine!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
 
Ok, does anyone have any freakin clue how this test is going to go down on Wed? I see the standard stuff from Deavers and guest lectues on written stuff but what about the EKG lectures? Is there still 4 questions per lecture and if so, does that mean that he will put 3 or 4 EKG's to read per lecture or will he have a number of written questions as well?? The reason I'm confused is because he has like 2 pages or so on his lecture notes. And the DPM's had 2 questions per lecture on their cardio they just completed. Not a lot to test on. Can a third or fourth year chime in on this first Cardio exam?? Anyone..................:scared:


Man, second year blows goats.
 
jbone said:
Ok, does anyone have any freakin clue how this test is going to go down on Wed? I see the standard stuff from Deavers and guest lectues on written stuff but what about the EKG lectures? Is there still 4 questions per lecture and if so, does that mean that he will put 3 or 4 EKG's to read per lecture or will he have a number of written questions as well?? The reason I'm confused is because he has like 2 pages or so on his lecture notes. And the DPM's had 2 questions per lecture on their cardio they just completed. Not a lot to test on. Can a third or fourth year chime in on this first Cardio exam?? Anyone..................:scared:


Man, second year blows goats.
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crap.....theres EKG's on this test?
 
3 questions per lecture. 'About 60 questions or so' per Dr. Hoff.
 
Anybody know what's up with Notepool #16? Was there some sort of lecture change and it's included in another note set or has it just not been completed yet? Thanks!
 
jbone said:
Ok, does anyone have any freakin clue how this test is going to go down on Wed? I see the standard stuff from Deavers and guest lectues on written stuff but what about the EKG lectures? Is there still 4 questions per lecture and if so, does that mean that he will put 3 or 4 EKG's to read per lecture or will he have a number of written questions as well?? The reason I'm confused is because he has like 2 pages or so on his lecture notes. And the DPM's had 2 questions per lecture on their cardio they just completed. Not a lot to test on. Can a third or fourth year chime in on this first Cardio exam?? Anyone..................:scared:



Man, second year blows goats.
Click to expand...

I am no Dr. Hoff but, just from going through my review book, it seems there is a lot of questions you can ask based on just one ECG. He could ask rate, is it normal sinus, what is the deviation, if there is a dysfunction what is it, what would you typically notice with X dysfunction or Y dysfunction, how big is the QRS complex/PR interval ect. I think he will go that route rather than have 90 ECGs on the test; after all, if the handouts are any judge, the print from copied ECGs looks like a 2 year old drew it (I can bearly see an R-wave let alone tell you how large it is).
 
Jamers said:
I am no Dr. Hoff but, just from going through my review book, it seems there is a lot of questions you can ask based on just one ECG. He could ask rate, is it normal sinus, what is the deviation, if there is a dysfunction what is it, what would you typically notice with X dysfunction or Y dysfunction, how big is the QRS complex/PR interval ect. I think he will go that route rather than have 90 ECGs on the test; after all, if the handouts are any judge, the print from copied ECGs looks like a 2 year old drew it (I can bearly see an R-wave let alone tell you how large it is).
Click to expand...
Agreed; we may see a lot of EKG's, but I'm sure not every question will be "Diagnose this patient's rhythm." As jamers said, there are a lot of other questions that can be asked about a particular EKG.
 
Jamers said:
I am no Dr. Hoff but, just from going through my review book, it seems there is a lot of questions you can ask based on just one ECG. He could ask rate, is it normal sinus, what is the deviation, if there is a dysfunction what is it, what would you typically notice with X dysfunction or Y dysfunction, how big is the QRS complex/PR interval ect. I think he will go that route rather than have 90 ECGs on the test; after all, if the handouts are any judge, the print from copied ECGs looks like a 2 year old drew it (I can bearly see an R-wave let alone tell you how large it is).
Click to expand...

Yeah, all I kept thinking to myself was 'I never realized EKGs were recorded with a crayon'.
 
This just in:

Dear first years,
Second year sucks...BIG TIME!
Enjoy your 12 lecture exams and time off for sleep and showering.

Love,
Jbone
 
jbone said:
This just in:

Dear first years,
Second year sucks...BIG TIME!
Enjoy your 12 lecture exams and time off for sleep and showering.

Love,
Jbone
Click to expand...

no joke! after the wonderfully depressing cardio exam tomorrow I get slammed with labs Wed ( labs, meetings til 5:00), thursday ( labs from 1 - 6:30), friday ( labs from 1 -6:30)..... and oh yeah... we have a pharm test and harvey practical monday

happy happy joy joy!
 
jbone said:
This just in:

Dear first years,
Second year sucks...BIG TIME!
Enjoy your 12 lecture exams and time off for sleep and showering.

Love,
Jbone
Click to expand...

I'm glad there's something exciting to look forward to during our second year. Thanks for the heads-up!!! 🙂
 
jbone said:
This just in:

Dear first years,
Second year sucks...BIG TIME!
Enjoy your 12 lecture exams and time off for sleep and showering.

Love,
Jbone
Click to expand...

So you're saying that if something smells a little funny in the library...it's probably the 2nd year sitting behind you?
 
thejanitor99 said:
no joke! after the wonderfully depressing cardio exam tomorrow I get slammed with labs Wed ( labs, meetings til 5:00), thursday ( labs from 1 - 6:30), friday ( labs from 1 -6:30)..... and oh yeah... we have a pharm test and harvey practical monday

happy happy joy joy!
Click to expand...

I'm not as bad off as you, by any means, but we have OMM tomorrow (you know there will be a quiz), lab and I have my ever so rewarding GI simulation this week.

In related news, I am going to take off tomorrow night to watch the Cubs got stomped. I hate them so much...👎
 
thejanitor99 said:
no joke! after the wonderfully depressing cardio exam tomorrow I get slammed with labs Wed ( labs, meetings til 5:00), thursday ( labs from 1 - 6:30), friday ( labs from 1 -6:30)..... and oh yeah... we have a pharm test and harvey practical monday

happy happy joy joy!
Click to expand...

I'm not as bad off as you, by any means, but we have OMM tomorrow (you know there will be a quiz), lab and I have my ever so rewarding GI simulation this week.

In related news, I am going to take off tomorrow night to watch the Cubs get stomped. I hate them so much...👎
 
thejanitor99 said:
no joke! after the wonderfully depressing cardio exam tomorrow I get slammed with labs Wed ( labs, meetings til 5:00), thursday ( labs from 1 - 6:30), friday ( labs from 1 -6:30)..... and oh yeah... we have a pharm test and harvey practical monday

happy happy joy joy!
Click to expand...
I was feeling ok about the rest of this week until you reminded me that we have a Pharm test on MONDAY! Are you freaking kidding me!? And OMM quiz tomorrow (most likely) means I can't go back to bed for the rest of the day after Cardio... 🙁

As an aside, I failed the "post-Spal encounter checklist" yet somehow got >100% on my write-up. How does that happen? I sure am glad they made me come to the review today, I learned a lot.
 
djnels01 said:
well, looks like it's family practice for me...
Click to expand...

tank-owned.jpg

pwned111.jpg


That is all I have to say. Ouch.
 
Dang....I haven't seen those forever Jbone...<3 ya!
 
djnels01 said:
I was feeling ok about the rest of this week until you reminded me that we have a Pharm test on MONDAY! Are you freaking kidding me!? And OMM quiz tomorrow (most likely) means I can't go back to bed for the rest of the day after Cardio... 🙁

As an aside, I failed the "post-Spal encounter checklist" yet somehow got >100% on my write-up. How does that happen? I sure am glad they made me come to the review today, I learned a lot.
Click to expand...


I am also in that Failing at over 100% group, as are a few other people I know of. Someone told me that some people that they know who didn't do so well on the SOAP note passed the checklist, while others who did really well on the SOAP note failed the checklist. Interesting...
 
theunc31 said:
I am also in that Failing at over 100% group, as are a few other people I know of. Someone told me that some people that they know who didn't do so well on the SOAP note passed the checklist, while others who did really well on the SOAP note failed the checklist. Interesting...
Click to expand...

From what I understand: a person looks over your video and, if they don't like something, marks you on it. However, you don't lose any points. I don't understand this but, I know a lot of people who were told to come in because they had failed that part only to find out they scored in the upper 90's. Pretty confused by the whole process. Well, I hope everyone else is in the "didn't fail cardio but, really thinking about that elective final," boat and not the, "oh **** I thought ECG meant Extra Cool Guy..." one.
 
I'd like to apologize for cardiology exam 1. It sounds like it was just as bad last year. I wonder how many people in your class quickly learned to use the ORANGE DUBIN book rather than hoff's notes.

Sry to all those who did bad. I did too on exam I.
Fortunately for you and me I did the makeup final and ended up with a 89 for the course.

Don't be dumb and not take the final. The questions are (for the most part) repeats from the first two exams so make sure you goto the exam reviews to know your mistakes.
 
Anyone know why the "best" place to listen for aortic regurgitation is over the tricuspid area?
 
AR is best heard in the Tricuspid region b/c when the blood "drips" back through the incompetent leaflet/s, it is moving in a direction most closely associated w/ Tricuspid area. Part of the other reason that I hear Cardiologist quote is that b/c of the position of the heart, the blood then hits the IV septum creating a sound heard over the Tricuspid area.

Just remember that you always hear things better when listening downstream of the movement of blood.
 
So DHT causes hair growth as part of it's androgenic effects...

And anti-androgens can be used therapeutically to help grow hair for those with alopecia... ie Finasteride (which lowers DHT by blocking 5a-reductase) causes hair growth as well as treating BPH...

I don't get it. DHT causes hair growth and hair loss?
 
djnels01 said:
So DHT causes hair growth as part of it's androgenic effects...

And anti-androgens can be used therapeutically to help grow hair for those with alopecia... ie Finasteride (which lowers DHT by blocking 5a-reductase) causes hair growth as well as treating BPH...

I don't get it. DHT causes hair growth and hair loss?
Click to expand...

I don't think I understood any of those lectures - adrenal steroids/androgens.
 
The GI sim lab was an excellent experience. I enjoyed applying things I've learned and felt it was a nice gauge of my performance. I liked how I didn't need to worry about points and could just focus on the patient. I felt this helped it to be a better means of personal assessment compared to a SPAL video. I hope for next year they keep it grade free, too. I have personally reviewed this simulation more in my mind than I have any of the SPALs. I'm looking forward to the next one.
 
djnels01 said:
So, what are everyone's thoughts on GI sim lab?
Click to expand...

I was also a huge fan of the Sim Lab. I wasn't looking forward to it, but was presently surprised. I agree with the above poster that it was nice to apply what we've learned. I'll take a Sim Lab over a SPAL any day of the week. It felt less staged than the SPAL and was a really good experience. Plus, Kolbinger basically left the door open for us to stop by and practice stuff whenever we want, which I thought was really nice.
 
So for those that attended SPAL preview on Friday... how were we supposed to know what the patient had? Was it the random bouts of PAT that she was experiencing? I thought any MV disease made you more prone to Atrial Tachy's, not just what she was diagnosed with by Wattleworth. I seriously don't know how else you would come to the conclusion she did-
 
djnels01 said:
So for those that attended SPAL preview on Friday... how were we supposed to know what the patient had? Was it the random bouts of PAT that she was experiencing? I thought any MV disease made you more prone to Atrial Tachy's, not just what she was diagnosed with by Wattleworth. I seriously don't know how else you would come to the conclusion she did-
Click to expand...

She based her conclusion on the presentation of the patient (age and symptoms).
 
It's possible that I heard something wrong or that my mind is so full of Cardio that I can't interpret anything, but did I understand correctly when they said that the 'match' in November is only on a State basis now? So basically we're picking a State to match into without knowing the hospitals we may be doing our 3rd year at...

Thanks
 
theunc31 said:
It's possible that I heard something wrong or that my mind is so full of Cardio that I can't interpret anything, but did I understand correctly when they said that the 'match' in November is only on a State basis now? So basically we're picking a State to match into without knowing the hospitals we may be doing our 3rd year at...

Thanks
Click to expand...

That's how I understood it. If that's true, it completely negates their reasoning for not letting us know exactly where we'll be until sometime in the Spring (Sites can get out of contracts up to 6 months before the start time).

How can I pick a state, if I know nothing about the sites there?? Hopefully November 5th they will be able to accurately and clearly answer all of our questions....
 
Ok, honestly...........

How many of you out there can still feel their face?

Not me.
 
jbone said:
Ok, honestly...........

How many of you out there can still feel their face?

Not me.
Click to expand...

I can't. I'm glad Cardio is over and done with though!

Another question: How many of you are totally weirded out by the fact that there's now a DMU Class of 2012 thread?
 
theunc31 said:
I can't. I'm glad Cardio is over and done with though!

Another question: How many of you are totally weirded out by the fact that there's now a DMU Class of 2012 thread?
Click to expand...
here here, I'm also rejoicing at the death of the beast that was Cardio. Is there seriously a 2012 DMU thread? Man we're getting old...
 
djnels01 said:
here here, I'm also rejoicing at the death of the beast that was Cardio. Is there seriously a 2012 DMU thread? Man we're getting old...
Click to expand...

DJ, it was an honor to watch you deliver that SIM baby the other day. My wife is due at the end of November and I already told our doctor that you will be delivering our child. See you there 😉

As for "the replacements"....thank the Lord!!!!!! Soon, they will come and we will not be here! 😀😀😀
 
jbone said:
DJ, it was an honor to watch you deliver that SIM baby the other day. My wife is due at the end of November and I already told our doctor that you will be delivering our child. See you there 😉

As for "the replacements"....thank the Lord!!!!!! Soon, they will come and we will not be here! 😀😀😀
Click to expand...

I was just listening to the first anticoagulant lecture, and I have a quick question.

Does rapid HIT occur in heparin naive pts., or pts. that have previously been on it, taken off for a long time, then put back on Heparin?

He first said that rapid HIT occurred w/ heparin naive pts., then he said the exact opposite at the end of that slide...

Any help would be awesome.

Good luck studying to everyone.
 
How I understood it was that it was either in heparin naive pts or if only small time had lapsed between doses.

slower response is if they have been off it for a long time.

It'sElectric said:
I was just listening to the first anticoagulant lecture, and I have a quick question.

Does rapid HIT occur in heparin naive pts., or pts. that have previously been on it, taken off for a long time, then put back on Heparin?

He first said that rapid HIT occurred w/ heparin naive pts., then he said the exact opposite at the end of that slide...

Any help would be awesome.

Good luck studying to everyone.
Click to expand...
 
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