Function of Lipase - TPR Demo Test

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7+ Year Member
May 3, 2016
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I am reviewing my TPR Demo Test results and can't seem to figure out this question even though it seems pretty straight-forward:

Lipase works to hydrolyze which of the following functional groups?
(a) Amide
(b) Ester
(c) Ether
(d) Hemiacetal

I originally thought the answer would be b - Ester as lipase hydrolyzes lipids; however, the answer is (a) Amide. Can someone please explain this? Thanks

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Are you sure the answer is (a), because lipases are enzymes that breakdown lipids. Lipids are made up of ester bonds with glycerol (alcohol) and a long chain fatty acid (carboxylic acid)?