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Hi all,
Just wondering if someone could please explain the process of iatrogenic hyperadrenocorticism to me? My understanding is that therapeutic glucocorticoids cause atrophy of the adrenals due to the negative feedback loop, downregulation of ACTH etc etc. So why would atrophy result in hyper rather than hypoadrenocorticism?
Apologies for what would probably be a very silly question of my brain wasn't so frazzled from revision! Thank you in advance to anyone who can help! Apologies as well if this is in the wrong place on the forum.
Just wondering if someone could please explain the process of iatrogenic hyperadrenocorticism to me? My understanding is that therapeutic glucocorticoids cause atrophy of the adrenals due to the negative feedback loop, downregulation of ACTH etc etc. So why would atrophy result in hyper rather than hypoadrenocorticism?
Apologies for what would probably be a very silly question of my brain wasn't so frazzled from revision! Thank you in advance to anyone who can help! Apologies as well if this is in the wrong place on the forum.