As I detailed above, we've had a pretty good experience with Compulink. There have been bumps in the road, but overall it's good, especially for the price. Our managing partner is now on the advisory board, trying to help them improve certain aspects. It's very customizable and they've been very receptive to suggestions.
Fact is that most systems will be click heavy (unless you prefer hotkeys, which I don't). We actually invested in touch screens, hoping to utilize that type of interface over mouse clicks. Was too difficult. We were having a lot of fat fingered errors in entry. Everyone is pretty much mouse, except the front office folks who were used to hotkeys from our prior PM system.
I've heard good things about MedFlow, but it is pretty expensive. Not familiar with OIS/Merge. My understanding about SRSoft is that it's a hybrid system with a lot of scanning of documents, rather than data entry. Makes it faster, but I suspect it will be problematic with meaningful use.
What you need to understand is all of these systems are a major adjustment. You can only adapt the systems to a degree. It's more on you to adapt yourself to the system. Once you've been doing paper charts for years, it's a shock to switch, but it's doable. I recommend slow implementation. Start with the PM, then new patients only (should only be 7-10 per day for most docs). That will give the techs/staff time to get used to the system. Finally, gradually introduce established patients in groups (e.g., last name A-C). Also, it's okay to hold onto the paper charts as a safety blanket, until you have your established patients firmly in the system. It's too difficult to review scanned charts in the system. Using this approach, we experienced very little slowdown in patient volume.
If you want more info, PM me, and I'd be happy to discuss it with you.