morning sickness

[canavarim]

Hi Guys , please someone help me with this question ... what is the best strategy to deal with pregnancy induced Nausea ?? Do you recommend any meds. like Emetrol and is it safe ??
I appreciate your answers

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[amy2003uva]

Ondansetron (Zofran) is the best, hands down. It's pregnancy category B, so completely safe. It also went generic recently so it is also much more cost effective.

 

[Global Disrobal]

You can always employ behavioral changes before progressing to pharmacologic agents. With respect to the latter, Ginger and B6 are good adjuncts to Reglan, Phenergan, and Zofran. A good trick, which I use with my patients, is to give the Reglan per vagina rather than PO.

If pharmacologic agents fail, then you must ensure that another etiology is not in play (thyroid, pancreas, etc). Be cautious with GD Tubes or PICC lines as new prospective data supports long existing retrospective findings confirming high rates of comlication.

Best of luck!

 

[MaddieMay]

Ondansetron (Zofran) is the best, hands down. It's pregnancy category B, so completely safe. It also went generic recently so it is also much more cost effective.

Zofran made me so constipated I thought I was going to die. I would have sworn I was impacted. Only took 2 doses, too. It's one of the listed side effects, but hopefully you won't have the same experience.

 

[abcabc]

Unisom (doxylamine) available over the counter!

It is used in Canada and other parts of the world along with B6 for morning sickness (look up diclectin). It was also available in the US till it was pulled off the market because the company couldn't afford the lawsuits - although there was no evidence that it caused any abnormalities. It is VERY safe and has been used for YEARS. (It used to be bendectin in the US I believe - you can do a google search).

This is after trying ginger, mints, eating small frequent meals, crackers, pretzels, sea-bands etc of course.

 

[Global Disrobal]

To piggy-back on that, there is a new RCT launched in the states looking at Diclectin being run out of UTMB, Magee, MedStar. Hopefully the results will allow the use of this regimen again.