You can e-submit after completing your personal statement,classes, EC's, etc. You do not have to have all your Recommendation letters received or the PCAT. Pharmcas will forward these as they are received. But they will not mail out your application until your transcripts arrive and are verified. If you are in no hurry, I would wait until everything is complete.
I am applying to a school with rolling admissions and they will start interviewing as soon as they have a completed file. That is why I wanted to be one of the first applications mailed.