I personally commuted 1.25 hours each way all four years 4-5 days per week. It sucks a lot. It was an easy drive, just long. And a huge waste of time (overall I think it was worth it obviously). It is doable, but difficult because driving becomes a part-time job. You will spend 15-20 hours in the car, which is time you can't spend studying, you can't spend socializing, you can't spend working. Your friends will sip their fresh hot coffee and brag about waking up at 820 for the 830 class while you cry inside that you woke up at 600 and have already downed 2-3 cups. I tried recording lectures and listening to them in the car to review but ultimately stopped because I didn't find it helpful. Many times I left 30-60 minutes early to guarantee I made it to class/exams during inclement weather. You'll have long days with an 0830 class and a 1500 lab and nothing between. It gives you time to study, but sucks you're "stuck" at school. And it will be hard on your car too, my commute was an even 700 miles per week. Depending on the volatility of gas prices and your mileage that can be an extra $1000-$4000 per year in gas alone. Don't forget new tires, frequent oil changes, paying for parking, and anything else your car might need depending on it's reliability. And you'll probably get fatter. I put on a good 15-20 lbs from the extra 15 hours/week I was sitting on my butt doing nothing but holding a steering wheel straight. I never want to do it again. And all of this is with amazing family/financial support (I used loans for school but my wife handled all other bills) and few other major stressors in my life.
Hopefully this provides some insight to long commutes to school, sorry it's pretty disjointed.
tldr: You can, it's horrible.
