We learned from mostly Powerpoints, but I'm still in my first year. I know that most students just download the Powerpoints and take notes underneath each slide. I think only one student uses her tablet to take notes directly on the slide. A lot of students like printing out all the slides, but that can be very expensive. We have access to free printing from another university, and that is the only reason that I print out some of the powerpoint slides.
I've been printing 6 slides per page, but some people print 2 or 3 per page. It's hard to see some figures, but I can read most of the information. Some classes use too many photos, so it wouldn't be useful for me to print those slides out (like Anatomy and Kinesiology).
I would see how much your school charges for printing.
I usually keep one 1.5 inch binder in my backpack with all the current handouts for all my classes, because I mostly use my laptop. At home, I'll have more binders for the older handouts that I don't need to take to class every day. Many classmates use a planner, but I just use Google Calendar so that I always have my planner with me (on my computer or on my phone). I recommend getting college-ruled paper and solid white computer paper for drawing on, dividers for the binder, post-it notes, index cards (if you want to make flashcards), a bunch of pens or colored pencils in different colors (my favorite are the Staedtler Triplus Fineliner Pens), stapler, printer, 3-hole puncher, highlighers and a whiteboard and whiteboard markers.