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I am curious to know what people think about this TED talk
I am curious to know what people think about this TED talk
The trouble is we don't know which genes cause a lot of these effects, and finding then would be a costly endeavour. We just aren't at the point yet where we can use genetics instead of race to determine treatment options. Someday we will be, and this will be a non-issue, but until then, her whole talk is nonsense.This is so interesting! I think she makes some great points (plenty of self-identified black people might have 50% or more "Caucasian" dna). Also, my SO is from Ethiopia, and was recently prescribed a med that "tends to work better in African Americans". But his genes might be dramatically different than your average African American.
I do think science needs to have the freedom to explore trait/heritage-linked diseases (eg. red heads risk of melanoma and Ashkenazi Jewish population risk of Tay-Sachs). And while these are better framed in terms of genetics, trying to communicate to the public about them would be difficult if we could only talk about such-and-such a gene, which the average person may or may not know they have.
Why should I care what a lawyer thinks about medicine outside of the courtroom?
Her talk isn't about medical school admissions at all, it's about doctors using race as a factor in diagnosing and treating patients and whether or not this practice is useful and beneficial.There are a number of valid reservations about how race is used in medical school admission and whether it is beneficial to medicine as a whole. The points she brings up are not amongst them.
Her talk isn't about medical school admissions at all, it's about doctors using race as a factor in diagnosing and treating patients and whether or not this practice is useful and beneficial.
This lady is ****ing stupid. She has no idea what's she talking about.
Some things are so obviously stupid that only very smart people can do the intellectual gymnastics necessary to convince themselves that they are true.She's an alum of Yale and Harvard so I don't think stupid is correct, but I'll say this Ted talk is one of the worse ones I've seen.
She's an alum of Yale and Harvard so I don't think stupid is correct, but I'll say this Ted talk is one of the worse ones I've seen.
The trouble is we don't know which genes cause a lot of these effects, and finding then would be a costly endeavour. We just aren't at the point yet where we can use genetics instead of race to determine treatment options. Someday we will be, and this will be a non-issue, but until then, her whole talk is nonsense.
Some things are so obviously stupid that only very smart people can do the intellectual gymnastics necessary to convince themselves that they are true.
I never said her talk had any evidence or credibility (in fact I agree that it's largely founded on her own preconceived notions and not on any sort of research). However, I was merely pointing out that her talk was not about medical school admissions, which, regardless of its merit, it is clearly not.But she doesn't have any credibility on that subject. She demonstrates that in her talk. She has no clinical background at all. The most credence she gives to any of her points (other than racism is bad) is that "I've been told that" without ever mentioning a name, a research paper, or any data whatsoever.
How you managed to do this off-the-cuff is beyond me. Guess I should've majored in philosophy 😛This is really the takeaway. No reason to take up arms in righteous anger. She has identified some research questions we are very familiar with and are actively working on. "Personalized medicine" is already reaching buzzword status. Her talk does reveal a lack of appreciation for the art of medicine, which requires the physician to draw from both evidence, heuristic and individual judgement. For a lawyer speaking at TED (which tends to have an educated audience) her argument is remarkably simplistic. A freshman philosophy student could dismantle it in a couple of minutes. That being said, there are some honest points in the talk which is, overall, lacking. It's basically one massive straw man with slippery slopes peppered throughout.
My first thoughts:
Her first point about how race is used in medical diagnosis started off talking about how the lazy handling of a variable might compromise the results (which I think is a valid critique, although I would have to know more about the goals of the study to say anything) but then moves on to make claims about how this means that taking race into consideration during a diagnosis is bad. I could see how you could get from A --> B here but it reduces a multidimensional and complicated mental process to a robotic, one-dimensional algorithm predicated on a single variable which is obviously garbage; if this point were to be effective, she is missing a lot of connective tissue and thought and this deficit is repeatedly present throughout the talk.
Similarly, her talk about diagnostic tools, measurements and drugs which take race into account ignores the scientific fact which she, in other places, relies on to make her argument: people's bodies are different. Yes, the main driver is not "race", which means a lot of things and nothing at the same time, but genetics (which are often but not necessarily tied to one's race). She first asserts that "wow doctors think black people's bodies are substandard" and uses an anecdote about a black lady saying "give me the drug white people are taking" to further this point. In the first case, she is clearly on a slippery slope. That is not at all what those diagnostic measurement standards are saying. They are saying, broadly, people's bodies are different and people of a certain background tend to present some things differently than others. There is more wrong with this point: the example of GFR is poor. She presents the numbers 86 and 89 and then says "wow look at this difference based on race" but we have no medical context for what those numbers mean. Is 3 points a really big difference? They are both in the normal range so is the difference truly important? Not to mention the fact that she once again pretends physicians are robots either do not or cannot exercise judgement. The example about the old lady is even worse. She later admits that race is tied to complex socio-economic factors which have consequences for a population's health but ignores these very same socio-economic factors which lead to patients mistrusting a drug. Sure, maybe this drug was **** and maybe the trial was not very good but the old lady anecdote tells us nothing about that. It's a red-herring attempting to appeal to a "common sense" approach to medicine when the reality is far more complicated.
Then there is this deal about the justifications for the measurements. The example with GFR she says is due to the assumption that black people have more muscle mass. She then says "well what about a white female body builder, I think she will have more muscle mass than me". No ****, your physician will probably pick up on that and interpret your GFR accordingly because (once again she is reducing the diagnostic process to a single-variable algorithm) he not only knows your particular condition but also the reason behind the different GFR standards and can put two and two together to conclude that your GFR standard might be closer to the number for non AAs than AAs. It's like a "heuristic" (which I know is a super common term in sociology and behavior science) is supposed to be a rigid algorithm and that's not the case. Straw man, moving on.
I'm not even going to touch the Cartwright example because her reasoning is so awful and specious there.
It's also remarkable to me that someone so concerned with history does not even understand that "evidence-based" medicine is basically in its infancy. In many respects we are very poor at practicing true evidence based medicine in that we dont have a large volume of evidence for every possible permutation of variables on the planet and our scientific understanding of many disease mechanisms is also lacking, if you do not understand that part of the art of medicine is dealing with how much you don't know then you have not thought very hard about a very important and obvious concept. The fact that we need to improve in this area is a valid critique but its not groundbreaking. Everyone understands we need to do better. Many many good, smart people are doing everything they can to make that a reality and those same people appreciate the importance of multi-hidden variables like race, SES, etc.
How you managed to do this off-the-cuff is beyond me. Guess I should've majored in philosophy 😛
This is really the takeaway. No reason to take up arms in righteous anger. She has identified some research questions we are very familiar with and are actively working on. "Personalized medicine" is already reaching buzzword status. Her talk does reveal a lack of appreciation for the art of medicine, which requires the physician to draw from both evidence, heuristic and individual judgement. For a lawyer speaking at TED (which tends to have an educated audience) her argument is remarkably simplistic. A freshman philosophy student could dismantle it in a couple of minutes. That being said, there are some honest points in the talk which is, overall, lacking. It's basically one massive straw man with slippery slopes peppered throughout.
Well said. Yes, she wandered outside of her area of expertise, and it's fair to call her out on incorrect or incomplete statements. However, I'm a little concerned by the rabid nature of a lot these responses. If a lawyer (or other intelegent non-medical person) had a valid and well-researched critique of the way medicine relates to race, I would want to hear it. I'm happy to hear reasonable critiques of her conclusions, but less happy to see this, "why is a lawyer talking about medicine."
Well said. Yes, she wandered outside of her area of expertise, and it's fair to call her out on incorrect or incomplete statements. However, I'm a little concerned by the rabid nature of a lot these responses. If a lawyer (or other intelegent non-medical person) had a valid and well-researched critique of the way medicine relates to race, I would want to hear it. I'm happy to hear reasonable critiques of her conclusions, but less happy to see this, "why is a lawyer talking about medicine."
Well, imagine something you're really passionate about, something you have dedicated your life to. Then have someone come in and criticize it publicly. Then imagine that person not only has poorly thought out arguments and facts but has no experience in the field whatsoever. Would you not be offended? I'm all for criticizing something but you better damn well have good facts to support it not just some made up bull**** she seemed to have cherry picked from history.
Of course it's easy to get riled up when someone criticizes something that you're passionate about. But here's how I see it: Firstly, she was criticizing something rather specific (the use of race as a medical category) not medicine as a whole, so unless you're publishing research about GFR differentials by race, I wouldn't take it too personally. Secondly, I'd almost say that the less cohesive her argument is, the less threatening it is. People have pointed out several obvious holes in her reasoning, which in my opinion makes her criticism that much less concerning.
I'm not a physician yet, so I'm sure that makes it easier for me to brush it off. I watched the video and noticed some weak arguments (they weren't all obvious to me right away), but was more interested in the questions she was asking, and where these types of questions might lead medical research in the future. It probably doesn't make a lot of sense for her to be lecturing on this topic as an "expert", but I'm happy for her to be pursuing the ideas she's pursuing.
I completely agree that there are times when particular medical treatments or procedures are informed by race. However, she does bring up an interesting point about biracial/multiracial individuals. Do we assume that someone who is 1/4 African American and 3/4 Caucasian will respond to a treatment the way African-Americans did in a study, just because they might self-identify (or we visually identify them) as black? Our social understanding of race can impact how we understand and apply the research that's available. I wouldn't call this race-baiting.Oddly enough, I see it the complete opposite of you. She used the GFR and bidil example to attack the art of medicine and how physicians practice as a whole. She's basically saying that we shouldn't use race as a factor in making decision making at all and that's completely false. People's race does matter because their genetics will have some differences despite being 99.9% equal relative to the rest of the human race.
A quick read on antihypertensive differences in African Americans. Skip to section 3.3 regarding the specific rebuttal for her bidil example.
http://www.medscape.com/viewarticle/740380_4
African American men have also been known to have a higher risk for prostate cancer. Prostate screening guidelines recommend to screen them at an earlier age.
http://www.stanford.edu/~alicesw/FreedmanProcNASSep2006.pdf
But did she address this at all? No. She conveniently just addressed that there are anti hypertensive drugs marketed for blacks without addressing the research behind it. I'm an anesthesia resident and in anesthesia there's a well known term called "Asian airway". This basically means that Asians, especially Asian females, have really anterior airways and short jaws that make them more challenging to intubate. This could potentially lead to deadly consequences if you're not aware and not prepared to secure their airway. Is this always the case? No, but surprisingly more often than not. Does this make me sexist and anti-asian? I don't think so since I'm actually thinking about my patient's best interest.
So, to me the less cohesive the argument the more insulting it is when people try to criticize something they poorly understand.
This race-baiting stuff has been way too common in today's society. People just choose examples that support their ideology and conveniently ignore or misinterpret everything else.
I completely agree that there are times when particular medical treatments or procedures are informed by race. However, she does bring up an interesting point about biracial/multiracial individuals. Do we assume that someone who is 1/4 African American and 3/4 Caucasian will respond to a treatment the way African-Americans did in a study, just because they might self-identify (or we visually identify them) as black? Our social understanding of race can impact how we understand and apply the research that's available. I wouldn't call this race-baiting.
Sent from my Nexus 5 using SDN mobile app
Enlighten us then.So many people here are missing the point of this talk. I feel so much second-hand embarrassment from reading these posts.
Her talk isn't about medical school admissions at all, it's about doctors using race as a factor in diagnosing and treating patients and whether or not this practice is useful and beneficial.
Enlighten us then.
Oh right, that argument again. Then I'll repeat my original statement that I don't think you know anything about race, genetics or how the two are used in medicine. Race roughly correlates with the genetic variance we see in humanity.Race is a social construct. Biologists acknowledge that there is no biological component to race. Therefore, treatments should not be tailored to race. I feel like if a geneticist made this same argument that people here would agree. However, SDN has some weird hard-on against social sciences. That is all I will say, because just like any time race gets mentioned on SDN, it turns into a ****show, and I have more important things to worry about.
Race is a social construct. Biologists acknowledge that there is no biological component to race. Therefore, treatments should not be tailored to race. I feel like if a geneticist made this same argument that people here would agree. However, SDN has some weird hard-on against social sciences. That is all I will say, because just like any time race gets mentioned on SDN, it turns into a ****show, and I have more important things to worry about.
That's literally the only post in this thread that mentioned admissions in any form. The other comments and the talk itself were referring to race in medical practice.yeah, but you wouldn't have clicked this thread if we weren't talking about admissions.
Oh right, that argument again. Then I'll repeat my original statement that I don't think you know anything about race, genetics or how the two are used in medicine. Race roughly correlates with the genetic variance we see in humanity.
Maybe know what you're talking about before implying that others are ignorant next time?
I'm not seeing how this rebuts my statement that "race roughly correlates with the genetic variance we see in humanity."It's a little more complex than that. Historically, yes, genetic pools would correlate to what we see as racial and ethnic groups. And as I said before, I do agree that some "race" or trait based medicine makes sense (@getdown gave a great example about "Asian airway".) However one thing that the speaker talks about is how we perceive people of mixed race. Our society still generally accepts the Jim Crow assertion that "one drop" of "black" blood makes a person black. So identifying someone by our social understanding of race might not provide the best estimate of their genetics.
It's a little more complex than that. Historically, yes, genetic pools would correlate to what we see as racial and ethnic groups. And as I said before, I do agree that some "race" or trait based medicine makes sense (@getdown gave a great example about "Asian airway".) However one thing that the speaker talks about is how we perceive people of mixed race. Our society still generally accepts the Jim Crow assertion that "one drop" of "black" blood makes a person black. So identifying someone by our social understanding of race might not provide the best estimate of their genetics. It's an important idea to consider.
I'm not seeing how this rebuts my statement that "race roughly correlates with the genetic variance we see in humanity."
Do you assume that every doctor is a ***** or something?
Edit: for niceness sake
This race-baiting stuff has been way too common in today's society. People just choose examples that support their ideology and conveniently ignore or misinterpret everything else.
Oh right, that argument again. Then I'll repeat my original statement that I don't think you know anything about race, genetics or how the two are used in medicine. Race roughly correlates with the genetic variance we see in humanity.
Maybe know what you're talking about before implying that others are ignorant next time?
Not an argument -- you're still not saying anything. I can't argue against vague abstractions. I know this is hard, but if you want to convince me that "race is a social construct" you are going to have to explain to me what that means and why you believe it. Stumbling in here with your fingers in your ears and your nose in the air isn't going to impress anyone.Considering this exact topic has come up in my genetics, general bio, and 2 public health classes, and they have all echoed what I've stated, I'll have to continue to disagree with you. I get it, you really want to be a doctor so naturally your confirmation bias and lack of understanding on the subject is clouding your judgment. But what do I know, I'm apparently just race baiting because I agree that blanket statements about an entire race of people aren't the best way to approach patient care.
Not an argument -- you're still not saying anything. I can't argue against vague abstractions. I know this is hard, but if you want to convince me that "race is a social construct" you are going to have to explain to me what that means and why you believe it. Stumbling in here with your fingers in your ears and your nose in the air isn't going to impress anyone.
Considering this exact topic has come up in my genetics, general bio, and 2 public health classes, and they have all echoed what I've stated, I'll have to continue to disagree with you. I get it, you really want to be a doctor so naturally your confirmation bias and lack of understanding on the subject is clouding your judgment. But what do I know, I'm apparently just race baiting because I agree that blanket statements about an entire race of people aren't the best way to approach patient care.
I don't need to cater to your ignorance by explaining basic sociological concepts to you. Go take an intro to soc class.
If you don't know anything then why are you spewing this conjecture? This isn't a humanities class in your liberal arts college -- evidence is a must.
Ill one-up you and say pubmed is your friend.
Great! Then it should be easy for you to explain such basic concepts about race to a dullard like myself.Yes, me not wanting to explain concepts that you should have learned freshman year
Great! Then it should be easy for you to explain such basic concepts about race to a dullard like myself.
Il wait🙂
Oh the ironyAfter reviewing your post history, it is apparent that this is falling of deaf ears. I'm sure you will interpret this as me backing down and you will revel in your little internet victory, but I hope at some point in your life you actually challenge your narrow mindset. You sound like a real joy to be around.
I'm fine with thatAlright guys, first article that popped up on google.
http://www.the-scientist.com/?articles.view/articleNo/38950/title/On-Race-and-Medicine/
Yes, race is linked to genetics.
Yes, genetics are more complex than our social view of race.
Yes, our understanding of race can still be medically relevant until further genetic understanding is reached.
Yes, we need to be careful of racial generalizations in medicine, especially as stereotypical racial groups intermix.
I think that nicely sums up all of our respective arguments.