Hi guys, i have trouble understanding the differences between oxidative phosphorolation and substrate level phosophorolation. I know ATP are the products for both just not grasping the oxidative and substrate meaning. Help.
thankshaha i was just going over this today...
substrate level phosphorylation takes place in glycoloysis and the krebs cycle where ATP is formed by direct transfer of phospate to ADP with the help of enzymes.
oxidative phosphorylation on the other had occurs in ETC where oxidation of nutrients is coupled with transfer of phosphate to ADP to for ATP.
Basically the difference is that with substrate level, there is a direct transfer of phospate to adp to form atp and with oxidative, nutrients need to be oxidized (meaning they need to lose electrons) to form ATP. During oxidative phosphorylation, electrons are transferred from electron donors to electron acceptors such as oxygen in a redox reaction. These redox reactions release energy, which is used to form ATP.
to put it as simply as possible; substrate level = direct, oxidative = oxidation of nutrients, releasing electrons that undergo redox reactions which releases energy that is used to form ATP
hope that helps haha. =)