This Q was originally posted by rayman on 4-18-2010 in the thread -
Lets discuss Q's of NBDE 1 (which is still open but locked for new posts)
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By rayman
hi
which of these is a nucleotide?
A-RIBOSE
B-URACIL
C-ADENOSINE
D-THYMIDYLATE
THANK IN ADVANCE
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@ rayman - Ans- D-THYMIDYLATE
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As part of an experimental study, a volunteer agrees to have 10 grams of mannitol injected intravenously. After sufficient time for equilibration, blood is drawn and the concentration of mannitol in the plasma is found to be 65mg/100 mL. Urinalysis reveals that 10% of the mannitol had been excreted into the urine during this time period. What is the approximate extracellular fluid volume of this volunteer?
A. 10 L
B. 14 L
C. 22 L
D. 30 L
E. 42 L
Thanks.
The ability to concentrate urine varies among animal species. The max urine conc that can be produced by an animal is MOST closely relate to which of the foll:
a. renal blood flow
b. total number of nephrons
c. gfr
d. length of loop of henle
e. diameter of distal tubule
You are right. Thanks. How would you explain this:
Insulin increases the activity of which of the foll:
a. enolase
b. phosphorylase
c. PFK
d. glucose 6 phosphatase
e. fructose 16 diphosphatase
yes u are right..insulin stimulate phosphofructosekinase and glucagon inhibit it.PFK-1 is also inhibited by citrate and ATP.Hey Jalika,
Let's think this through, So insulin has an anabolic effect right? So it tends to favor glucose transport, uptake and glycogen syntheses. So if we look at the answers give. I would say insulin inhibits gluconeogenesis enzymes which are d & e. It also inhibits glycogen breakdown. SO it inhibits glycogen phosphorylase, so there goes answer b. My guess would be that it stimulates glycolysis and break down of glucose in the target cell.I think the answer is (c). Please anyone correct me if I am wrong.
volume=(amount injected-amount excreted)/concentrationp.msonormal, li.msonormal, div.msonormal { margin: 0in 0in 0.0001pt; font-size: 10pt; font-family: "times new roman"; }div.section1 { page: Section1; }
as part of an experimental study, a volunteer agrees to have 10 grams of mannitol injected intravenously. After sufficient time for equilibration, blood is drawn and the concentration of mannitol in the plasma is found to be 65mg/100 ml. Urinalysis reveals that 10% of the mannitol had been excreted into the urine during this time period. What is the approximate extracellular fluid volume of this volunteer?
A. 10 l
b. 14 l
c. 22 l
d. 30 l
e. 42 l
I am thinking it's d. as the contercurrent mechanism for concentrating urine depends on the thick ascending loop of henle and the resorption of Na, K, and Cl into the medulla. If you have another answer please share. I might be wrong.
yes, you are right.the answer should be loop of henleythe answer should be loop of henley cause the highest osmolar conc of the urine occurs in the loop of henley and if its length is increased it would def help it..this is applied in desert animals whose loop of henley length is increased as to facilitate increased water reabsorption..
the answer should be loop of henley cause the highest osmolar conc of the urine occurs in the loop of henley and if its length is increased it would def help it..this is applied in desert animals whose loop of henley length is increased as to facilitate increased water reabsorption..
Thanks.
The ability to concentrate urine varies among animal species. The max urine conc that can be produced by an animal is MOST closely relate to which of the foll:
a. renal blood flow
b. total number of nephrons
c. gfr
d. length of loop of henle
e. diameter of distal tubule
Its PFK... in the liver once the ATP has been generated and Citrate levels hv risen thnx to the Krebs cycle.. inorder to synthesize fatty acids the insulintakes over --> generation of PFK2---> production Fructose 2, 6 bisphosphate.. this complex overrides the negative effects of Citrate and ATP on PFK1 and the glycolysis continues to produce Acetyl Co A which the in turn produces Acetyl Co A----> Fatty Acid SynthesisYou are right. Thanks. How would you explain this:
Insulin increases the activity of which of the foll:
a. enolase
b. phosphorylase
c. PFK
d. glucose 6 phosphatase
e. fructose 16 diphosphatase
Very interesting Insulin also is responsible for the glycogen synthase which results in storage of glucose as glycogen.. so it simultaneously activate two contradicting enzymes in presence of excess glucose.. PFK2 and glycogen synthase!! probably the initial response is to increase the glycogen storesIts PFK... in the liver once the ATP has been generated and Citrate levels hv risen thnx to the Krebs cycle.. inorder to synthesize fatty acids the insulintakes over --> generation of PFK2---> production Fructose 2, 6 bisphosphate.. this complex overrides the negative effects of Citrate and ATP on PFK1 and the glycolysis continues to produce Acetyl Co A which the in turn produces Acetyl Co A----> Fatty Acid Synthesis
Hey dentdoc,
i think they are right on the countercurrent multiplier and length of loop of Henle..
i have a question here
In the molar, the rootcanals usually join the pulp chamber
a) at level of furcation
b)at varying levels depending on age
c)within the cervical third of crown
d)apical to cervical level of crown
Key ans is c.. decks answer is d... plz explain
, please answer these questions ASAP as I am taking my test in two days!
What kind of fungal infection affects reticuloendothelial cells
Thanks!
please answer these questions ASAP as I am taking my test in two days!
Failure of fusion in what processes causes oblique clefting of the face
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Essentially fungal infections such as cryptococcosis, coccidiomycosis, blastomycosis and histoplasmosis are granulomatous diseases 🙂Ans: Histoplasmosis - H. capsulatum
The dimorphic yeast cells are found within the macrophages
Thanx Dr Bunty 🙂hey correct ans should be D........
i have seen this que at 2 different spaces......and ans is different at both places......i have confirmed in willers.....
What hormone acts slowly and acts on intracellular receptors? Estrogen
(I dont think estrogen is the correct answer, is it)
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Insulin and IGF have what in common? tyrosine kinase receptor, membrane receptor (I think its tyrosine kinase...but basically they were trying to ask what kind of second messenger is used)Thanks!
h2o216. The sanger method of cloning uses
-transcription
-translation
-reverse transcriptase
17. Intermediate in synthesis of cholesterol
-squalene 👍
-doxycholine
-choline
12. Sucrose directly contributes to plaque by
-polysaccharides 👍
-glycolytic enzymes
-mucin
10. What type of hemoglobin do diabetic patients have?
-hbf
-hba
-hbaic 👍
-hbs
11. Most abundant proteoglycan in teeth
-chondroitin sulfate 👍... Not sure though
-hyaluronate
1. Methylated labile protein
-thf
-sam
 (i think) -methionine
2. Aa with hydroxyl group
-serine 👍
-alanine
-arginine (i think)
24. Cigarette smoking does not contribute to the cancers in: Larynx, stomach, esophagus, pancreas, bladder... I think there was a colon too in the question.. Ca colon... Smoking.. Does not affect
igg is activated where? Plasma cells produce ig g in the medullary cords
1. Bacteria lacking catalase are sensitive to ... Oxygen or superoxide ion or hydrogen peroxide?
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risk factor for development of endometrial carcinoma --> high levels of estrogen, nulliparity, late meno pause
orgin of trigeminal n
communication from facial vein to cavernous sinuse? superior ophthalmic V via angular V
if posterior crossbite which cusps would contacts in mediotrussive movement??? buccal of mand and buccal of maxillary as well.. though there should be no contracts on mesiotrusive side
muscles with least regenerative capacity skeletal muscle
if V nerve is cut below medulla what happens
loss of sensation of pain same side....> ipsilateral loss of pain and propioception ( same side)..
loss of pain ipsilateral
loss of propioception same side
loss of sensation of propioception opposite side
sensory nucleus for 5 6 9 7 and 10 is Spinal tract nucleus... but not for 6.. its a purely motor nerve... remember SO4 LR6--->>6 AB ducter
1 L question 363.. plz explain
42 year old lady with hyperparathyroidism.....
Which will be most likely increased in this case??
My answer.. Ca absorption..
Key answer, renal Ca excretion... why???
👍 🙂 Thnxyes hyper parathyroidism also increase ca absorption........
because of osteoclastic activity ca level of blood is so high...kidney reabsorb ca as maximum as it can but it's still beyond it's absorption capacity....so excess will be excreted.....
serous demilunes secrete into: intercalated ducts, striated ducts etc.? mixed salivary glands eg. submandibular salivary gland
FL longitudinal section of canine is taken, where is the widest portion of the pulp chamber? Medial 1/3 or cervical 1/3
Cervical 1/3rd
Where is pain from the orofacial region sent to? Nucleus ambiguous, nucleus dorsal, some other choices, inferior olive
Spinal nucleus of V
A dentist loses a tooth, where should he not look for it? Vallecula, piriform recess, pharyngeal recess, and something else by the larynx
pharyngeal recess
Where is testosterone made…not which cell, but where in the system, seminiferous epithelium?
Crypts of lieberkuhn are in what layer of the SI? Muscularis externa, adventitia, submucosal?
lamina propria.. between the villi
Anterior superior most position of condylar head is known as: centric relation
I know CR is posterior superior what is anterior superior?
thats right, it is sup ant
To get to submandibular duct you need to cut through: mucosa only
shouldnt it be mylohyoid or something?
its the duct, not the gland 🙂
Two questions on which groove is bigger max 2nd pm or max 1st pm, and which has more supplemental grooves
max 1st premolar groove is longer
What stimulates the ectoderm to turn into neural crest?
Hi guys,
I need help with this question:
The apices of a mandibular second molar are located:
a-posteriorly to ptergomandubular raphe
b- inferiorly to mylohyoid muscle insertion 👍
the other 2 are not correct. Which one is it?? the answer key says b but could it be (a) too? what do u think?
Pterygomandibular raphe is further posteriorly placed
Should be glucose 6 phosphate.. not sureWhat is key charac about mand 1st molar? Mesiolingual developmental groove ML goove.. mandibular first premolar
this isnt right because isnt that the key characteristic of max first molar and premolar? Max first premolar mesial groove extends to marginal ridge
Cortical plate histologically has: I dont remember, one answer was Whorling bone cortical bone is compact bone
blood supply of condyle? Deep temporal and massetric branches of maxillary artery
fumarate is in what two pathways Kreb's cycle, urea cycle
which of the following when metabolized is largest drop in free energy? Creatine phosphate, glucose 6 phosphate i think its this
h2o2
Should be glucose 6 phosphate.. not sure
Hi guys,
I need help with this question:
The apices of a mandibular second molar are located:
a-posteriorly to ptergomandubular raphe
b- inferiorly to mylohyoid muscle insertion
the other 2 are not correct. Which one is it?? the answer key says b but could it be (a) too? what do u think??
ans should be creatin phosphate.......
because delta G is measurement of release of energy in reaction.....creatin phosphate contain maximum energy in it's phosphate bond so it will release maximum energy....and the drop of free energ of substance will me maximun
anaita have u taken the date for test?......
some facts abt hemoglobin in diabetics , it's HbA1c(not HbAic)
Glycated hemoglobin (glycosylated hemoglobin, hemoglobin A1c, HbA1c, A1C, or Hb1c; sometimes also HbA1c) is a form of hemoglobin which is measured primarily to identify the average plasma glucose concentration over prolonged periods of time. It is formed in a non-enzymatic glycation pathway by hemoglobin's exposure to plasma glucose. Normal levels of glucose produce a normal amount of glycated hemoglobin. As the average amount of plasma glucose increases, the fraction of glycated hemoglobin increases in a predictable way. This serves as a marker for average blood glucose levels over the previous months prior to the measurement