Bis-GMA111 Full Member Verified Member 10+ Year Member Army Jul 28, 2011 #1 Advertisement - Members don't see this ad if a grignard can be used to attack an epoxide, why can't it be used to attack a regular ether?
Advertisement - Members don't see this ad if a grignard can be used to attack an epoxide, why can't it be used to attack a regular ether?
F FROGGBUSTER Full Member 10+ Year Member Jul 28, 2011 #2 What kind of reaction do you think would happen between a Grignad and ether? Ring opening can occur between a Grignard and an epoxide, nothing happens between a Grignard and ether. This is why ethers are good solvents from Grignards. Upvote 0 Downvote
What kind of reaction do you think would happen between a Grignad and ether? Ring opening can occur between a Grignard and an epoxide, nothing happens between a Grignard and ether. This is why ethers are good solvents from Grignards.
indigenoustw Am I picking my nose or showing my shaka? 10+ Year Member Jul 28, 2011 #3 Angle strain makes it easy for Grignard to attack epoxides. Other forms of ether are pretty stable and most are free of angle strain. Upvote 0 Downvote
Angle strain makes it easy for Grignard to attack epoxides. Other forms of ether are pretty stable and most are free of angle strain.
wired202808 Membership Revoked Removed 10+ Year Member 5+ Year Member 15+ Year Member Aug 8, 2011 #4 preDENT1210 said: if a grignard can be used to attack an epoxide, why can't it be used to attack a regular ether? Click to expand... An Ether has no acidic protons for the grignard to attack. Upvote 0 Downvote
preDENT1210 said: if a grignard can be used to attack an epoxide, why can't it be used to attack a regular ether? Click to expand... An Ether has no acidic protons for the grignard to attack.