The rule of thumb is given culture data, step-down to the narrowest therapy possible for as short a duration as possible. Obviously this isn't possible for empiric therapy, given the lack of culture data. Most of the time you don't need to step down empiric therapy, as no infection is identified and you can just stop antibiotics.Thanks. Sorry for the confusion, I just meant antibiotics in general.
I gave a example of ashtma for patients on advair diskus, which is a long acting beta and steroid together, when patient is on it for a long time without any ashtma attacks you can step down their advair to a steroid alone.
I was wondering what kind of antibiotics you discharge the patients on after empirical IV therapy. I guess to be simple, it is from a broad spectrum to narrow spectrum right? I was hoping to see some websites that can help me with this. But thank you for the ISDA recommendation .