Hi JDPharmD,
Most of us on this thread are entering 1st year pharmacy students, so we can't really tell you what all the ins and outs of the pharmacy school are yet. As a person who has grown up in LA all my life, I can tell you that, USC, as you've heard, is located in the "ghetto", or more technically East LA. The area immediately surrounding the school is not that safe, but outlying neighborhoods, where most health science students live anyway (alhambra, monterey, pasadena) are reasonably priced and safe. There is a growing Asian-American population in Alhambra and Monterey Park, so if you like Asian-type food you'll be in for a treat. Family housing would more likely be located near the University campus (undergrad) located about 5-10 miles West of the health science campus, so if you decided to live there, you'd have to take a bus/shuttle to get to school, or drive.
I applied to all the schools you mentioned, and got in to both UCSF and USC (UOP waitlisted me and I didn't go to the SD interview). My main reasons for going to USC were the dual degree programs that were offered (trying to get a PharmD/MBA), 4 yrs at USC suited me better (I anticipate I'll need the summers to intern and find out my niche in pharmacy), flexibility of their curriculum (SC changes their coursework every so often to suit the needs of the students, and it doesn't use the "if it still works, don't fix it" mentality that I think other pharm schools may have), networking abilities (50% of pharmacists in SoCal are graduates of USC pharm school, plus the comraderie I've witnessed this past week with the drug list makes me feel so happy), and of course, being close to my family and friends.
Hope this helps. PM me if you have any other questions.