If you could choose a dental related masters thesis topic, what would it be?

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If I could choose (and I know this is a big topic and unrealistic for a thesis as I have been told LOL) I would be curious to see how vaping impacts the oral microbiome and if it differs to how smoking cigarettes impacts the oral microbiome
 
I would probably want to look at medication interactions and the oral microbiome.
 
A great topic that one of my friends in my D1 class actually used was the benefits of chewing gum on ones oral health. Surprising how many benefits there were, even without only using sugar free gum. Very interesting topic, very relatable for many readers.
 
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