NBDE part 1- jan/feb/march 2011 test takers

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NKDmed

NKDmed

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Hi everyone whose appearing for the nbde part 1 for jan or feb (or anytime early next year).. Im starting this thread so that we can all motivate each other, and keep each other updated on our progress. so that we dont get lazy, but rather stick to schedule and stay focussed.

**Please dont ask for books, or material or study partners in this thread.

Lets keep it solely for
1. Motivating each other
2. Sharing any mistakes or tips to study better
3. Asking questions during preparation
4. Anything you wish to share with others while you are studying
5. Review or questions regarding books, decks, tests that you are using during this study period

Thanks, and i wish good luck to my fellow test takers 🙂
 
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dentdoc10 said:
I knew, it had to be steroid hormones since they are protein bound and protein's are large polar molecules are not filtered into the glomerulus. and also was sure that the conc of small non-polar solutes is the same in the plasma and the filtrate.
The rest of the explanation that I have put up is what i researched to make sure I was right and thought I might as well share it.
I haven't taken a date yet, for the test. I noticed that u have been actively solving Q's on SDN and I couldn't solve quite a few of them myself and had to read through the explanation's. So, I'm in no way ready for the test...and I still have a subject to complete😳. Appreciate ur comment though.
Click to expand...
Actuallly, i too am way behind plans but solving one paper of the subject i am studying helps me assess which topics have i inadvertantly missed from my reading 🙂 .. which subject left???
 
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dentdoc10 said:
Once a hormone is secreted into the blood stream by an endocrine tissue, depending on their solubility, few, that are readily soluble in blood are transported free but most are bound to a specific plasma protein carrier, with the complex being disseminated to distant tissues. Plasma carrier proteins exist for all classes of endocrine hormones. Carrier proteins for peptide hormones prevent hormone destruction by plasma proteases. Carriers for steroid and thyroid hormones allow these very hydrophobic substances to be present in the plasma at concentrations several hundred-fold greater than their solubility in water would permit. Carriers for small, hydrophilic amino acid-derived hormones prevent their filtration through the renal glomerulus, greatly prolonging their circulating half-life.
Hormones need to be metabolically converted from their biologically active form into an inactive one. Inactivation can occur at various stages of hormone action. Peripheral inactivation (e.g. by liver enzymes) is required to ensure steady-state levels of plasma hormones as steroids are more or less continuously secreted into the bloodstream. Moreover, if a hormone is to act as a " chemical signal ", its half-life in the circulation must be limited, so that any change in secretion rate is immediately reflected by a change in its plasma concentration (particularly when secretion rates are decreased). But hormone inactivation can also occur in target tissues, notably after the hormone has triggered the relevant biological effects in order to ensure termination of hormone action.
The main site of peripheral steroid inactivation and catabolism is the liver, but some catabolic activity also occurs in the kidneys. Inactive hormones are mainly eliminated as urinary (mostly conjugated with sulphate and/or glucuronide derivatives) metabolites. Usually, steroids are eliminated once they have been inactivated (i.e., they are not " recycled "). This elimination (e.g. as a urinary excretion products) requires conversion to hydrophilic compounds in order to ensure their solubility in biological fluids at rather high concentrations.
Glomerular filtrate has everything same as plasma except proteins. Steroid hormones , Thyroid hormones, Vitamins A, D, E, K all need protein as transporter to circulate in the blood.As there is no protein filtering into Glomerular filtrate, those Steroid hormones can not be filtered
Click to expand...

Each of the following characterises a peptide hormone EXCEPT

one option in it is"usually transported in unbound form in plasma'.. and correct answer is.." bind to intracellular receptor'... so we must keep in mind the fact that they can be transported in unbound form in plasma since they are water soluble when answering the question..... just thought i must share this with you
 
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Anaita said:
What is the net charge on glutamic acid at a PH of 1?
a- +2
B- +1
C- 0
d- -1
e- -2
Glutamic Acid is an amino acid with an acidic chain but hw would one determine its net charge at pH 1 (very low pH so will be in protonated ie + form) but hw does one calculate the charge.. plz explain
Click to expand...
????:scared:
 
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Polyuridylic Acid in a cell free system capable of protein synthesis results in production of polyphanylalanine. In this system polyuridylic acid functions as
a)DNA
b) transfer RNA
c)m RNA
c) rRNA
d)mt RNA......
plz help!!!phenylalanine... catecholamine synthesis...answer given is mRNA.. why not mt RNA???😳😕
 
Last edited:
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Anaita said:
Each of the following characterises a peptide hormone EXCEPT

one option in it is"usually transported in unbound form in plasma'.. and correct answer is.." bind to intracellular receptor'... so we must keep in mind the fact that they can be transported in unbound form in plasma since they are water soluble when answering the question..... just thought i must share this with you
Click to expand...
Same applies to all amine hormones which are water soluble except thyroid hormone which is lipid soluble.
 
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Anaita said:
Polyuridylic Acid in a cell free system capable of protein synthesis results in production of polyphanylalanine. In this system polyuridylic acid functions as
a)DNA
b) transfer RNA
c)m RNA
c) rRNA
d)mt RNA......
plz help!!!phenylalanine... catecholamine synthesis...answer given is mRNA.. why not mt RNA???😳😕
Click to expand...

Polyuridylic acid carries the codon and is the template for polyphenylalanine synthesis - which is what mRNA stands for. In option d) it just says mt RNA and doesnt specify what kind of mtRNA. This is what I think.
Most of the DNA is present in the nucleus and very little in the mitochondria, and so most of the replication & transcription takes place in the nucleus. Out of the 3000 protiens the mitochondria host, only 13-14 of them are coded on the mtDNA that are involved in theelectrons transport chain , 2 rRNA subunits and 22 tRNA molecules (all necessary for protein synthesis). Electron transfer chain needs a lot more than 13 or 14, but the others are coded by the nuclear DNA. This means most of the genetic information coding for the protein makeup of mitochondria is in chromosomal DNA and is involved in processes other than ATP synthesis. Only about 3% of them code for ATP production proteins.
 
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👍👍
dentdoc10 said:
Polyuridylic acid carries the codon and is the template for polyphenylalanine synthesis - which is what mRNA stands for. In option d) it just says mt RNA and doesnt specify what kind of mtRNA. This is what I think.
Most of the DNA is present in the nucleus and very little in the mitochondria, and so most of the replication & transcription takes place in the nucleus. Out of the 3000 protiens the mitochondria host, only 13-14 of them are coded on the mtDNA that are involved in theelectrons transport chain , 2 rRNA subunits and 22 tRNA molecules (all necessary for protein synthesis). Electron transfer chain needs a lot more than 13 or 14, but the others are coded by the nuclear DNA. This means most of the genetic information coding for the protein makeup of mitochondria is in chromosomal DNA and is involved in processes other than ATP synthesis. Only about 3% of them code for ATP production proteins.
Click to expand...

Thanx so much... and we inherit only our mom's copy of mitochondrial DNA!!
 
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dentdoc10 said:
Polyuridylic acid carries the codon and is the template for polyphenylalanine synthesis - which is what mRNA stands for. In option d) it just says mt RNA and doesnt specify what kind of mtRNA. This is what I think.
Most of the DNA is present in the nucleus and very little in the mitochondria, and so most of the replication & transcription takes place in the nucleus. Out of the 3000 protiens the mitochondria host, only 13-14 of them are coded on the mtDNA that are involved in theelectrons transport chain , 2 rRNA subunits and 22 tRNA molecules (all necessary for protein synthesis). Electron transfer chain needs a lot more than 13 or 14, but the others are coded by the nuclear DNA. This means most of the genetic information coding for the protein makeup of mitochondria is in chromosomal DNA and is involved in processes other than ATP synthesis. Only about 3% of them code for ATP production proteins.
Click to expand...
Thanx so much... again...!! really appreciate your help
 
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Anaita said:
Actuallly, i too am way behind plans but solving one paper of the subject i am studying helps me assess which topics have i inadvertantly missed from my reading 🙂 .. which subject left???
Click to expand...

Yet to start Anatomy...R u done with ur first reading?
 
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Anaita said:
Done with my first reading.. but feel totally blank.... and have to do oral histo.... am planning on starting physio; followed by Anat
Click to expand...
So u remember all the codons of the human genome.... 🙂)... or have you got a tattoo of the human genome done???
 
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You people really made this a question answer thread 🙂 ... good going... anyways...anyone's result out yet??? haam, nkdmed ...??or any one else??
 
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bhavi4all said:
Nah i didnt... i just did the books we are told to do... i didnt do anything extra... but you can do... it might help...[/QUOTE
Thanx..Am sure gonna give it a skip as well..🙂
have a doubt... in the initial breakdown of glutamine in the muscle it is converted to alanine which is transported to the liver and there again goes back to pyruvate.. since glutamate being an AA with an acidic side chain will lower the pH of blood and hence alanine is transported to the liver... but alanine with its CH3 R group is a hydrophobic AA.. so is it carried to the liver through albumin... ????
Click to expand...
 
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I jus joined the forum.....but dun have much time left....exam of 25th april....lol...feel so underprepared.......anyone with me in april??
 
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Hi, I just joined today and I am going to register for next year to start this ....
Would you please tell me how many tests overall are required to finish?
Thank you.
 
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nbde25411 said:
I jus joined the forum.....but dun have much time left....exam of 25th april....lol...feel so underprepared.......anyone with me in april??
Click to expand...
Appearing in June... but you are not alone... we all share the same feelings... do shoot some tough questions you come across.......... wouild be a pleasure attempting answering them
 
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Anaita said:
So u remember all the codons of the human genome.... 🙂)... or have you got a tattoo of the human genome done???
Click to expand...

I didnt think we had to know each one of them....I just concentrated on the most commonly tested...i.e, the one's mentioned in decks/kaplan. Did u learn all of them? It wouldnt hurt to learn the whole table, i guess..u got me thinking..
 
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dentdoc10 said:
I didnt think we had to know each one of them....I just concentrated on the most commonly tested...i.e, the one's mentioned in decks/kaplan. Did u learn all of them? It wouldnt hurt to learn the whole table, i guess..u got me thinking..
Click to expand...
No... i don't think we have to...
 
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dentdoc10 said:
I knew, it had to be steroid hormones since they are protein bound and protein's are large polar molecules are not filtered into the glomerulus. and also was sure that the conc of small non-polar solutes is the same in the plasma and the filtrate.
The rest of the explanation that I have put up is what i researched to make sure I was right and thought I might as well share it.
I haven't taken a date yet, for the test. I noticed that u have been actively solving Q's on SDN and I couldn't solve quite a few of them myself and had to read through the explanation's. So, I'm in no way ready for the test...and I still have a subject to complete😳. Appreciate ur comment though.
Click to expand...
Another one... all steroid hormones are protein bound except DHEA and all peptide hormones circulate free in blood except IGF (Insulin like growth factor)....conditions under which steroid hormones are excreted from the kidney.. Nephrotic syndrome
 
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To all my SDN friends!!!

Thank you so much for your help and support during my study and afterward. Thanks for bhavi4all for his continuous worrying and asking about my results.
I decided to leave SDN for a while because my result got very late and I was under tremendous pressure from home, work duties and this endless report. Now, at this moment, I've received my score and I got 91\100.

where is the god damn it banana ??????

again thanks to all of you and I'm here to help anyone of you.
Good luck to anyone taking the exam my only advice, plz read carfully, and stick to the basic idea and never chase zebra.

oooh here i find it!!!!

:banana::banana::banana::banana::banana::banana::banana::banana::banana::banana::banana:
 
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Hey congrats buddy!! awesome score... proud of you .and thanks for mentioning my name there..lol.. i hope it was not sarcastic 😉 lol
Haam said:
To all my SDN friends!!!

Thank you so much for your help and support during my study and afterward. Thanks for bhavi4all for his continuous worrying and asking about my results.
I decided to leave SDN for a while because my result got very late and I was under tremendous pressure from home, work duties and this endless report. Now, at this moment, I’ve received my score and I got 91\100.

where is the god damn it banana ??????

again thanks to all of you and I’m here to help anyone of you.
Good luck to anyone taking the exam my only advice, plz read carfully, and stick to the basic idea and never chase zebra.

oooh here i find it!!!!
Click to expand...
 
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bhavi4all said:
Hey congrats buddy!! awesome score... proud of you .and thanks for mentioning my name there..lol.. i hope it was not sarcastic 😉 lol

NOOOOOOO of course not.
thank you from deep of my heart and i hope that we will meet again in postgrad👍
Click to expand...
 
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Hahah Haam I already took my exam. I ended up with an 89. Not as good as your result, but I am still happy with it .. just missed a 90 😀
 
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Haam said:
To all my SDN friends!!!

Thank you so much for your help and support during my study and afterward. Thanks for bhavi4all for his continuous worrying and asking about my results.
I decided to leave SDN for a while because my result got very late and I was under tremendous pressure from home, work duties and this endless report. Now, at this moment, I've received my score and I got 91\100.

where is the god damn it banana ??????

again thanks to all of you and I'm here to help anyone of you.
Good luck to anyone taking the exam my only advice, plz read carfully, and stick to the basic idea and never chase zebra.

oooh here i find it!!!!

:banana::banana::banana::banana::banana::banana::banana::banana::banana::banana::banana:
Click to expand...

Congrats Haam! that's a damn good score. I kept looking for ur posts for a while and sent u a couple of msg's. Finally I see it here...very happy for u...good luck with admissions.
 
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Haam said:
To all my SDN friends!!!

Thank you so much for your help and support during my study and afterward. Thanks for bhavi4all for his continuous worrying and asking about my results.
I decided to leave SDN for a while because my result got very late and I was under tremendous pressure from home, work duties and this endless report. Now, at this moment, I’ve received my score and I got 91\100.

where is the god damn it banana ??????

again thanks to all of you and I’m here to help anyone of you.
Good luck to anyone taking the exam my only advice, plz read carfully, and stick to the basic idea and never chase zebra.

oooh here i find it!!!!

:banana::banana::banana::banana::banana::banana::banana::banana::banana::banana::banana:
Click to expand...
congrates haam really nice to c ur good score
 
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Amreki said:
Hahah Haam I already took my exam. I ended up with an 89. Not as good as your result, but I am still happy with it .. just missed a 90 😀
Click to expand...
so soorry, you know i've been out for a while😀

it is amazing score, well done👍
 
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dentdoc10 said:
Congrats Haam! that's a damn good score. I kept looking for ur posts for a while and sent u a couple of msg's. Finally I see it here...very happy for u...good luck with admissions.
Click to expand...
yeah i have noticed that, thank you so much and believe me it means a lot to me 😍
 
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saara said:
congrates haam really nice to c ur good score
Click to expand...
thank you saara so much. hope that we all have admission to post grad.
BTW , i'm wondring where are NKMED, Being human? did they suicide:meanie:
i love to hear from them
 
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hi i would like to know how much approximately should i score to get above 85 percentile in nbde part 1 help plz..im givin my exmas in 1month so wud like to know...
NKDmed said:
Hi everyone whose appearing for the nbde part 1 for jan or feb (or anytime early next year).. Im starting this thread so that we can all motivate each other, and keep each other updated on our progress. so that we dont get lazy, but rather stick to schedule and stay focussed.

**Please dont ask for books, or material or study partners in this thread.

Lets keep it solely for
1. Motivating each other
2. Sharing any mistakes or tips to study better
3. Asking questions during preparation
4. Anything you wish to share with others while you are studying
5. Review or questions regarding books, decks, tests that you are using during this study period

Thanks, and i wish good luck to my fellow test takers 🙂
Click to expand...
 
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i took my exam on april 13 dont know what to say exactly i cant tell if the exam was eassy or hard some questions were pretty fine some were weired that is why i cant tell , im waiting for my result fingers crossed
 
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hi haam,
sorry for posting this late...thats an awsome score...i was actually shifting to us from my country and kind of got busy with the packing and stuff and not to forget the long flight and the jetlag i am suffering from...will give my exam soon too now...gudluck for ur admissions and congrats again...
 
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untillsoon said:
i took my exam on april 13 dont know what to say exactly i cant tell if the exam was eassy or hard some questions were pretty fine some were weired that is why i cant tell , im waiting for my result fingers crossed
Click to expand...
congratulaion.
i know how do you feel after the exam! it is a disaster.
goodluck in your score and keep it up:xf:
 
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Being human said:
hi haam,
sorry for posting this late...thats an awsome score...i was actually shifting to us from my country and kind of got busy with the packing and stuff and not to forget the long flight and the jetlag i am suffering from...will give my exam soon too now...gudluck for ur admissions and congrats again...
Click to expand...
finally you are here!!!
good for you, try to adapt to the weather changes too.:laugh:
anyhow, don't worry you will rock the exam just stay focus and revise as much as you can.
goodluck
 
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any recent update?
does anyone need any help?
goodluck to all of you who's taking the exam, and all who passed, get ready for the knocking cycle.
 
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im still waiting for my score , so worried, BTW ham when u finished ur exam did u expect to get this score i mean ur 91 did u expect more or less?
 
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to be honest, yes i did.😱
in any MCQs exam, i count out what i did guess and what i didn't know. after the exam, i ended by 48 MCQs. i do remember:idea:
one thing i was worried about is the wierd calculation of the exam.
but finally it went ok and i'm having this good score.

good bless you in your waiting, it really sucks.:laugh:
 
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