Let's say a school interviews from September through February and let's say that the same proportion of applicants are interviewed in each of those months. Six months means almost 17% interviewed in each month. Now let's say that invites go out 4 weeks before the range of dates offered for the interview. That would mean that the last invites would go out in mid -January and by now, mid-November, there would be Dec, Jan and Feb invites still to go out or about 50% of invites that have not yet gone out. In fact, if you factor in those who will turn down an offer because they already have a better offer of admission, it might be more than 50% of ii are yet to be issued.
The season isn't over by a long shot but if you haven't received even one offer by next Wednesday at 11:59 pm, you should spend the long weekend thinking about what you might do in 2017-2018 if this cycle does not yield at least one offer of admission. The Thanksgiving rule doesn't mean you won't get into medical school this cycle but it is the point at which you should start making contingency plans. (In contrast to the people who are ready to make contingency plans in mid-September because they haven't received an ii at that point.)