Academically, I did very well my first two years of college (including most of the pre-reqs, i.e. A's in Orgo), then basically bombed a handful of semesters... NF's, F's, C's. The reasons are unimportant here, but I touch on it in my personal statement. I took several years off school, then transferred to another university. I was there for three semesters, took 50 credits of almost entirely upper-level biology, and got all A's and two A-'s across 15 classes (so a 3.95 there) before graduating. However, the damage was already done, so I have a cGPA of 2.98, a sGPA of 2.93, and no realistic way of changing those because I'm already up around 150 credits.
I took the MCAT twice back in 2005 (yay pencil and paper version!), and got V13, P10, B11 (34R) in April, followed by V13, P12, B13 (38O) in August after actually preparing. I took it again last summer because my scores were too old, and was too cheap to void my score despite having the flu, so this time I racked up V11, P11, B11 (33 S). My advisor said not to risk retaking it, though it burns to score 5 points less than my high-water mark.
My EC's are decent (shadowing, hospital volunteering, 4 years on an EMS squad, employment as a phlebotomist), as are my LORs.